Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India
<p>Abstract</p> <p>Background</p> <p>Synthetic pyrethroids are potent insecticides most commonly used in the vector control programme. These are applied for indoor residual sprays, space sprays and in impregnated bed nets. Resistance reduces the efficacy of insecticides...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-06-01
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| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/9/1/179 |
| _version_ | 1818756942291533824 |
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| author | Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju |
| author_facet | Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju |
| author_sort | Dash Aditya P |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Synthetic pyrethroids are potent insecticides most commonly used in the vector control programme. These are applied for indoor residual sprays, space sprays and in impregnated bed nets. Resistance reduces the efficacy of insecticides. Thus, the susceptibility status of the target vector(s) is monitored routinely to select the effective ones. A study was undertaken in a malaria endemic coastal city Mangalore, Karnataka, South India, against the known malaria vector <it>Anopheles stephensi</it>.</p> <p>Methods</p> <p>The susceptibility status was assessed at diagnostic doses of DDT (4%), malathion (5%), deltamethrin (0.05%), cyfluthrin (0.15%), alphacypermethrin (0.10%), lambdacyhalothrin (0.05%) and permethrin (0.75%) using the standard WHO tube test method during October/November 2006.</p> <p>Results</p> <p><it>Anopheles stephensi </it>was resistant to malathion by 54.9%, but tolerant to deltamethrin by 86.1%, cyfluthrin 95.5% and alphacypermethrin 90.6%, whereas it was susceptible to DDT by 98.1%, lambdacyhalothrin 98.6% and permethrin 100.0%, respectively. The KDT<sub>50 </sub>and KDT<sub>95 </sub>values for these insecticides also showed the similar responses.</p> <p>Conclusion</p> <p>Susceptibility of <it>An. stephensi </it>to DDT is an important finding as this has never been used in Mangalore city, whereas its rural counterpart <it>Anopheles culicifacies </it>is widely resistant to this insecticide. The study explores the selection and rotation of the appropriate insecticide molecule even within the same group for effective vector management.</p> |
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| format | Article |
| id | doaj.art-d4c4016f64b84927b83f3fa5668518d8 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-18T06:03:03Z |
| publishDate | 2010-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-d4c4016f64b84927b83f3fa5668518d82022-12-21T21:18:38ZengBMCMalaria Journal1475-28752010-06-019117910.1186/1475-2875-9-179Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South IndiaDash Aditya POjha Vijay PGhosh Susanta KTiwari SatyanarayanRaghavendra Kamaraju<p>Abstract</p> <p>Background</p> <p>Synthetic pyrethroids are potent insecticides most commonly used in the vector control programme. These are applied for indoor residual sprays, space sprays and in impregnated bed nets. Resistance reduces the efficacy of insecticides. Thus, the susceptibility status of the target vector(s) is monitored routinely to select the effective ones. A study was undertaken in a malaria endemic coastal city Mangalore, Karnataka, South India, against the known malaria vector <it>Anopheles stephensi</it>.</p> <p>Methods</p> <p>The susceptibility status was assessed at diagnostic doses of DDT (4%), malathion (5%), deltamethrin (0.05%), cyfluthrin (0.15%), alphacypermethrin (0.10%), lambdacyhalothrin (0.05%) and permethrin (0.75%) using the standard WHO tube test method during October/November 2006.</p> <p>Results</p> <p><it>Anopheles stephensi </it>was resistant to malathion by 54.9%, but tolerant to deltamethrin by 86.1%, cyfluthrin 95.5% and alphacypermethrin 90.6%, whereas it was susceptible to DDT by 98.1%, lambdacyhalothrin 98.6% and permethrin 100.0%, respectively. The KDT<sub>50 </sub>and KDT<sub>95 </sub>values for these insecticides also showed the similar responses.</p> <p>Conclusion</p> <p>Susceptibility of <it>An. stephensi </it>to DDT is an important finding as this has never been used in Mangalore city, whereas its rural counterpart <it>Anopheles culicifacies </it>is widely resistant to this insecticide. The study explores the selection and rotation of the appropriate insecticide molecule even within the same group for effective vector management.</p>http://www.malariajournal.com/content/9/1/179 |
| spellingShingle | Dash Aditya P Ojha Vijay P Ghosh Susanta K Tiwari Satyanarayan Raghavendra Kamaraju Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India Malaria Journal |
| title | Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India |
| title_full | Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India |
| title_fullStr | Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India |
| title_full_unstemmed | Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India |
| title_short | Reduced susceptibility to selected synthetic pyrethroids in urban malaria vector <it>Anopheles stephensi</it>: a case study in Mangalore city, South India |
| title_sort | reduced susceptibility to selected synthetic pyrethroids in urban malaria vector it anopheles stephensi it a case study in mangalore city south india |
| url | http://www.malariajournal.com/content/9/1/179 |
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