A Novel Use of Allopurinol as A Quorum-Sensing Inhibitor in <i>Pseudomonas aeruginosa</i>

A Novel Use of Allopurinol as A Quorum-Sensing Inhibitor in <i>Pseudomonas aeruginosa</i>

<i>Pseudomonas aeruginosa</i> can cause a variety of healthcare-associated infections by its arsenal of virulence factors. Virulence factor production is largely controlled by the cell-to-cell communication system termed quorum sensing (QS). Targeting QS may be a good approach to inhibit...

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Bibliographic Details
Main Authors: Ahmed Al Saqr, Mohammed F. Aldawsari, El-Sayed Khafagy, Moataz A. Shaldam, Wael A. H. Hegazy, Hisham A. Abbas
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antibiotics
Subjects:
quorum sensing
allopurinol
virulence inhibition
<i>Pseudomonas aeruginosa</i>
Online Access:https://www.mdpi.com/2079-6382/10/11/1385

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