Natural antisense transcripts as drug targets

Natural antisense transcripts as drug targets

The recent discovery of vast non-coding RNA-based regulatory networks that can be easily modulated by nucleic acid-based drugs has opened numerous new therapeutic possibilities. Long non-coding RNA, and natural antisense transcripts (NATs) in particular, play a significant role in networks that invo...

Full description

Bibliographic Details
Main Authors: Olga Khorkova, Jack Stahl, Aswathy Joji, Claude-Henry Volmar, Zane Zeier, Claes Wahlestedt
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
natural antisense transcript (NAT)
long nocoding RNA
anisense oligonucleotides
posttranscriptional regulation
nucleic acid based therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.978375/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.978375/full

Similar Items