Natural antisense transcripts as drug targets
The recent discovery of vast non-coding RNA-based regulatory networks that can be easily modulated by nucleic acid-based drugs has opened numerous new therapeutic possibilities. Long non-coding RNA, and natural antisense transcripts (NATs) in particular, play a significant role in networks that invo...
Main Authors: | Olga Khorkova, Jack Stahl, Aswathy Joji, Claude-Henry Volmar, Zane Zeier, Claes Wahlestedt |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.978375/full |
Similar Items
-
Development of a rapid and inexpensive method to reveal natural antisense transcripts
by: Collani Silvio, et al.
Published: (2012-09-01) -
Asymmetric localization of natural antisense RNA of neuropeptide sensorin in Aplysia sensory neurons during aging and activity
by: Beena eKadakkuzha, et al.
Published: (2014-04-01) -
Nucleic Acid–Based Therapeutics in Orphan Neurological Disorders: Recent Developments
by: Olga Khorkova, et al.
Published: (2021-04-01) -
History of Research on Antisense Oligonucleotide Analogs
by: Jack S. Cohen
Published: (2021-03-01) -
Natural antisense transcripts in the biological hallmarks of cancer: powerful regulators hidden in the dark
by: Shanshan Zhao, et al.
Published: (2020-09-01)