Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas

Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas

Abstract Background Although intrinsic immune-evasion is important in cancer proliferation, metastasis and response to treatment, it is unclear whether intrinsic immune-evasion patterns of gliomas can aid in predicting clinical prognosis and determining treatment. Methods A total of 182 immune-evasi...

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Bibliographic Details
Main Authors: Zewei Tu, Qiankun Ji, Qing Han, Xiaoyan Long, Jingying Li, Lei Wu, Kai Huang, Xingen Zhu
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Cancer
Subjects:
Lower-grade glioma (LGG)
Prognosis
Cancer immune evasion
Immunotherapy response
Temozolomide (TMZ) sensitivity
Online Access:https://doi.org/10.1186/s12885-022-09984-5

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