Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience
(1) Background: The current study examined the correlations between platelet count (PC), spleen diameter (SD), and their ratio to establish a non-invasive technique for predicting the presence of oesophageal varices in cirrhotic patients. (2) Methods: The current study was an observational study con...
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MDPI AG
2024-01-01
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| Series: | Gastroenterology Insights |
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| Online Access: | https://www.mdpi.com/2036-7422/15/1/7 |
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| author | Srinith Patil Swarup Kumar Patnaik Manjit Kanungo Kanishka Uthansingh Jimmy Narayan Subhasis Pradhan Debakanta Mishra Manoj Kumar Sahu Girish Kumar Pati |
| author_facet | Srinith Patil Swarup Kumar Patnaik Manjit Kanungo Kanishka Uthansingh Jimmy Narayan Subhasis Pradhan Debakanta Mishra Manoj Kumar Sahu Girish Kumar Pati |
| author_sort | Srinith Patil |
| collection | DOAJ |
| description | (1) Background: The current study examined the correlations between platelet count (PC), spleen diameter (SD), and their ratio to establish a non-invasive technique for predicting the presence of oesophageal varices in cirrhotic patients. (2) Methods: The current study was an observational study conducted in the Gastroenterology Department at IMS and SUM Hospital from November 2019 to November 2021. Consecutive cirrhotic patients without a history of gastrointestinal bleeding were enrolled in the study, and the esophageal varices were assessed. The patients underwent the necessary tests, including upper gastrointestinal endoscopy, liver function testing, abdominal ultrasonography, and full hemograms. All these parameters were analyzed statistically through SPSS version 23, and <i>p</i> ≤ 0.05 was considered statistically significant. (3) Results: There were significant differences between cases with and without esophageal varices in the following parameters: PC, SD and their ratio, hemoglobin, and ALT level. The PC/SD ratio of ≤ 1400 was associated with a sensitivity of 90.9%, specificity of 80.8%, and a positive predictive value of 82.56% in predicting the presence of oesophageal varices, as per receiver operating curve (ROC) analysis in our study. (4) Conclusions: Esophageal varices can be predicted non-invasively using the platelet count, spleen diameter, and PC/SD ratio. |
| first_indexed | 2024-04-24T18:16:18Z |
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| id | doaj.art-d4cf8ca1a92e4b78a1459675180e12d4 |
| institution | Directory Open Access Journal |
| issn | 2036-7414 2036-7422 |
| language | English |
| last_indexed | 2024-04-24T18:16:18Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastroenterology Insights |
| spelling | doaj.art-d4cf8ca1a92e4b78a1459675180e12d42024-03-27T13:42:27ZengMDPI AGGastroenterology Insights2036-74142036-74222024-01-011519810610.3390/gastroent15010007Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center ExperienceSrinith Patil0Swarup Kumar Patnaik1Manjit Kanungo2Kanishka Uthansingh3Jimmy Narayan4Subhasis Pradhan5Debakanta Mishra6Manoj Kumar Sahu7Girish Kumar Pati8Department of Gastroenterology, ESIC Medical College & Hospital, Kalaburagi 585106, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, IndiaDepartment of Gastroenterology, Apollo Hospital, Bhubaneswar 751005, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan University, Bhubaneswar 751003, India(1) Background: The current study examined the correlations between platelet count (PC), spleen diameter (SD), and their ratio to establish a non-invasive technique for predicting the presence of oesophageal varices in cirrhotic patients. (2) Methods: The current study was an observational study conducted in the Gastroenterology Department at IMS and SUM Hospital from November 2019 to November 2021. Consecutive cirrhotic patients without a history of gastrointestinal bleeding were enrolled in the study, and the esophageal varices were assessed. The patients underwent the necessary tests, including upper gastrointestinal endoscopy, liver function testing, abdominal ultrasonography, and full hemograms. All these parameters were analyzed statistically through SPSS version 23, and <i>p</i> ≤ 0.05 was considered statistically significant. (3) Results: There were significant differences between cases with and without esophageal varices in the following parameters: PC, SD and their ratio, hemoglobin, and ALT level. The PC/SD ratio of ≤ 1400 was associated with a sensitivity of 90.9%, specificity of 80.8%, and a positive predictive value of 82.56% in predicting the presence of oesophageal varices, as per receiver operating curve (ROC) analysis in our study. (4) Conclusions: Esophageal varices can be predicted non-invasively using the platelet count, spleen diameter, and PC/SD ratio.https://www.mdpi.com/2036-7422/15/1/7esophageal varixportal hypertensionplatelet countspleen diameter |
| spellingShingle | Srinith Patil Swarup Kumar Patnaik Manjit Kanungo Kanishka Uthansingh Jimmy Narayan Subhasis Pradhan Debakanta Mishra Manoj Kumar Sahu Girish Kumar Pati Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience Gastroenterology Insights esophageal varix portal hypertension platelet count spleen diameter |
| title | Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience |
| title_full | Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience |
| title_fullStr | Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience |
| title_full_unstemmed | Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience |
| title_short | Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience |
| title_sort | platelet count spleen diameter ratio as a non invasive predictor of esophageal varices in cirrhotic patients a single center experience |
| topic | esophageal varix portal hypertension platelet count spleen diameter |
| url | https://www.mdpi.com/2036-7422/15/1/7 |
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