Remote-controllable bone-targeted delivery of estradiol for the treatment of ovariectomy-induced osteoporosis in rats

Remote-controllable bone-targeted delivery of estradiol for the treatment of ovariectomy-induced osteoporosis in rats

Abstract Background Osteoporosis (OP) is a systemic skeletal disease marked by bone mass reduction and bone tissue destruction. Hormone replacement therapy is an effective treatment for post-menopausal OP, but estrogen has poor tissue selectivity and severe side effects. Results In this study, we co...

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Bibliographic Details
Main Authors:	Yuanyuan Guo, Yongwei Liu, Chen Shi, Tingting Wu, Yongzhi Cui, Siyuan Wang, Ping Liu, Xiaobo Feng, Yu He, Dehao Fu
Format:	Article
Language:	English
Published:	BMC 2021-08-01
Series:	Journal of Nanobiotechnology
Online Access:	https://doi.org/10.1186/s12951-021-00976-4

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