Reno-Protective Effect of Low Protein Diet Supplemented With α-Ketoacid Through Gut Microbiota and Fecal Metabolism in 5/6 Nephrectomized Mice

Reno-Protective Effect of Low Protein Diet Supplemented With α-Ketoacid Through Gut Microbiota and Fecal Metabolism in 5/6 Nephrectomized Mice

BackgroundLow protein supplemented with α-ketoacid diet (LKD) was recommended to be an essential intervention to delay the progression of chronic kidney disease (CKD) in patients who were not yet on dialysis. Aberrant gut microbiota and metabolism have been reported to be highly associated with CKD....

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Bibliographic Details
Main Authors: Yifan Zhu, Haidong He, Yuyan Tang, Yinshun Peng, Ping Hu, Weiqian Sun, Ping Liu, Meiping Jin, Xudong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Nutrition
Subjects:
chronic kidney disease
low-protein diet supplemented with α-ketoacid
gut microbiota
fecal metabolism
renal fibrosis
5/6Nx mice
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.889131/full

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