Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs

In this study the authors identify localized RNAs in the Drosophila follicular epithelium by spatial transcriptomics and through genetic analyses determine canonical and translation-based mechanisms underlying basal and apical RNA localization.

Bibliographic Details
Main Authors: Lucia Cassella, Anne Ephrussi
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34004-2
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author Lucia Cassella
Anne Ephrussi
author_facet Lucia Cassella
Anne Ephrussi
author_sort Lucia Cassella
collection DOAJ
description In this study the authors identify localized RNAs in the Drosophila follicular epithelium by spatial transcriptomics and through genetic analyses determine canonical and translation-based mechanisms underlying basal and apical RNA localization.
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spelling doaj.art-d4dba8db7e7045859e735dc46594d90e2022-12-22T04:33:09ZengNature PortfolioNature Communications2041-17232022-10-0113111610.1038/s41467-022-34004-2Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAsLucia Cassella0Anne Ephrussi1European Molecular Biology LaboratoryEuropean Molecular Biology LaboratoryIn this study the authors identify localized RNAs in the Drosophila follicular epithelium by spatial transcriptomics and through genetic analyses determine canonical and translation-based mechanisms underlying basal and apical RNA localization.https://doi.org/10.1038/s41467-022-34004-2
spellingShingle Lucia Cassella
Anne Ephrussi
Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
Nature Communications
title Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
title_full Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
title_fullStr Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
title_full_unstemmed Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
title_short Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
title_sort subcellular spatial transcriptomics identifies three mechanistically different classes of localizing rnas
url https://doi.org/10.1038/s41467-022-34004-2
work_keys_str_mv AT luciacassella subcellularspatialtranscriptomicsidentifiesthreemechanisticallydifferentclassesoflocalizingrnas
AT anneephrussi subcellularspatialtranscriptomicsidentifiesthreemechanisticallydifferentclassesoflocalizingrnas