Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs
In this study the authors identify localized RNAs in the Drosophila follicular epithelium by spatial transcriptomics and through genetic analyses determine canonical and translation-based mechanisms underlying basal and apical RNA localization.
Main Authors: | , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34004-2 |
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author | Lucia Cassella Anne Ephrussi |
author_facet | Lucia Cassella Anne Ephrussi |
author_sort | Lucia Cassella |
collection | DOAJ |
description | In this study the authors identify localized RNAs in the Drosophila follicular epithelium by spatial transcriptomics and through genetic analyses determine canonical and translation-based mechanisms underlying basal and apical RNA localization. |
first_indexed | 2024-04-11T08:57:43Z |
format | Article |
id | doaj.art-d4dba8db7e7045859e735dc46594d90e |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-11T08:57:43Z |
publishDate | 2022-10-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-d4dba8db7e7045859e735dc46594d90e2022-12-22T04:33:09ZengNature PortfolioNature Communications2041-17232022-10-0113111610.1038/s41467-022-34004-2Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAsLucia Cassella0Anne Ephrussi1European Molecular Biology LaboratoryEuropean Molecular Biology LaboratoryIn this study the authors identify localized RNAs in the Drosophila follicular epithelium by spatial transcriptomics and through genetic analyses determine canonical and translation-based mechanisms underlying basal and apical RNA localization.https://doi.org/10.1038/s41467-022-34004-2 |
spellingShingle | Lucia Cassella Anne Ephrussi Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs Nature Communications |
title | Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs |
title_full | Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs |
title_fullStr | Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs |
title_full_unstemmed | Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs |
title_short | Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs |
title_sort | subcellular spatial transcriptomics identifies three mechanistically different classes of localizing rnas |
url | https://doi.org/10.1038/s41467-022-34004-2 |
work_keys_str_mv | AT luciacassella subcellularspatialtranscriptomicsidentifiesthreemechanisticallydifferentclassesoflocalizingrnas AT anneephrussi subcellularspatialtranscriptomicsidentifiesthreemechanisticallydifferentclassesoflocalizingrnas |