Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis
Objective To understand the expression of miR⁃155 in the periodontal ligament cell population of pa⁃ tients with chronic periodontitis. Methods Periodontal ligament cells from the teeth of patients (n = 11) with chronic periodontitis were isolated and cultured, as were periodontal ligament cells f...
| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | zho |
| Publicado em: |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2018-06-01
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| Colecção: | 口腔疾病防治 |
| Assuntos: | |
| Acesso em linha: | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.06.006 |
| _version_ | 1831759760826826752 |
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| author | ZHAO Hua LI Xianing ZENG Xianli ZHAO Hongyu |
| author_facet | ZHAO Hua LI Xianing ZENG Xianli ZHAO Hongyu |
| author_sort | ZHAO Hua |
| collection | DOAJ |
| description | Objective To understand the expression of miR⁃155 in the periodontal ligament cell population of pa⁃
tients with chronic periodontitis. Methods Periodontal ligament cells from the teeth of patients (n = 11) with chronic
periodontitis were isolated and cultured, as were periodontal ligament cells from intact teeth obtained from healthy pa⁃
tients (n = 13) who had been treated with orthodontic extraction (the control group). The expression level of miR⁃155 in
the two groups of periodontal ligament cell populations was detected by real⁃time fluorescence⁃based quantitative PCR.
Results The periodontal ligament cell expression level of miR⁃155 was significantly higher in the chronic periodontitis
group (0.93 ± 0.12) than in the control group (0.76 ± 0.25) (P < 0.01). Conclusion miR⁃155 expression in periodontal
ligament cells was obviously stronger in patients with chronic periodontitis. |
| first_indexed | 2024-12-22T02:52:32Z |
| format | Article |
| id | doaj.art-d4df9a9aa0964b51ac5db10b2f82ccbd |
| institution | Directory Open Access Journal |
| issn | 2096-1456 2096-1456 |
| language | zho |
| last_indexed | 2024-12-22T02:52:32Z |
| publishDate | 2018-06-01 |
| publisher | Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases |
| record_format | Article |
| series | 口腔疾病防治 |
| spelling | doaj.art-d4df9a9aa0964b51ac5db10b2f82ccbd2022-12-21T18:41:22ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562096-14562018-06-0126637037310.12016/j.issn.2096⁃1456.2018.06.006Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitisZHAO Hua0LI Xianing1ZENG Xianli2ZHAO Hongyu3Stomatological Hospital, Southern Medical UniversityDepartment of Periodontics, The First Affiliated Hospital of Zhengzhou University·School of Sto⁃ matology Zhengzhou University Shenzhen Stomatological Hospital of Southern Medical UniversityThe First Affiliated Hospital of Zhengzhou UniversityObjective To understand the expression of miR⁃155 in the periodontal ligament cell population of pa⁃ tients with chronic periodontitis. Methods Periodontal ligament cells from the teeth of patients (n = 11) with chronic periodontitis were isolated and cultured, as were periodontal ligament cells from intact teeth obtained from healthy pa⁃ tients (n = 13) who had been treated with orthodontic extraction (the control group). The expression level of miR⁃155 in the two groups of periodontal ligament cell populations was detected by real⁃time fluorescence⁃based quantitative PCR. Results The periodontal ligament cell expression level of miR⁃155 was significantly higher in the chronic periodontitis group (0.93 ± 0.12) than in the control group (0.76 ± 0.25) (P < 0.01). Conclusion miR⁃155 expression in periodontal ligament cells was obviously stronger in patients with chronic periodontitis.http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.06.006Chronic periodontitisPeriodontal ligament cell populationMicro RNAMicro⁃155Regulate |
| spellingShingle | ZHAO Hua LI Xianing ZENG Xianli ZHAO Hongyu Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis 口腔疾病防治 Chronic periodontitis Periodontal ligament cell population Micro RNA Micro⁃155 Regulate |
| title | Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis |
| title_full | Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis |
| title_fullStr | Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis |
| title_full_unstemmed | Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis |
| title_short | Expression of periodontal ligament cell population miR ⁃ 155 in patients with chronic periodontitis |
| title_sort | expression of periodontal ligament cell population mir ⁃ 155 in patients with chronic periodontitis |
| topic | Chronic periodontitis Periodontal ligament cell population Micro RNA Micro⁃155 Regulate |
| url | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.06.006 |
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