Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort

Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort

BackgroundCOVID-19 associated coagulopathy (CAC) is associated with an increase in thromboembolic events. Current guidelines recommend prophylactic heparins in the management of CAC. However, the efficacy of this strategy in the intensive care population remains uncertain.ObjectiveWe aimed to measur...

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Bibliographic Details
Main Authors: Tom W. van de Berg, Mark M. G. Mulder, Teba Alnima, Magdolna Nagy, Rene van Oerle, Erik A. M. Beckers, Tilman M. Hackeng, Anne-Marije Hulshof, Jan-Willem E. M. Sels, Yvonne M. C. Henskens, Iwan C. C. van der Horst, Hugo ten Cate, Henri M. H. Spronk, Bas C. T. van Bussel, MaastrICCht Collaborators
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
thrombin generation
COVID
anticoagulation
ICU
DOACs
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.929284/full

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