Protein Quality Control in the Nucleus
In their natural environment, cells are regularly exposed to various stress conditions that may lead to protein misfolding, but also in the absence of stress, misfolded proteins occur as the result of mutations or failures during protein synthesis. Since such partially denatured proteins are prone t...
Main Authors: | Sofie V. Nielsen, Esben G. Poulsen, Caio A. Rebula, Rasmus Hartmann-Petersen |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-07-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-273X/4/3/646 |
Similar Items
-
Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome
by: Amanda B. Abildgaard, et al.
Published: (2020-08-01) -
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
by: Amanda B Abildgaard, et al.
Published: (2019-11-01) -
Releasing the Lockdown: An Emerging Role for the Ubiquitin-Proteasome System in the Breakdown of Transient Protein Inclusions
by: Yuval Reiss, et al.
Published: (2020-08-01) -
Mitochondrial Protein Quality Control Mechanisms
by: Pooja Jadiya, et al.
Published: (2020-05-01) -
Quality control of cytoplasmic proteins inside the nucleus
by: Lion Borgert, et al.
Published: (2022-01-01)