Untangling Species-Level Composition of Complex Bacterial Communities through a Novel Metagenomic Approach

Untangling Species-Level Composition of Complex Bacterial Communities through a Novel Metagenomic Approach

ABSTRACT 16S small-subunit (SSU) rRNA gene-based bacterial profiling is the gold standard for cost-effective taxonomic reconstruction of complex bacterial populations down to the genus level. However, it has been proven ineffective in clinical and research settings requiring higher taxonomic resolut...

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Bibliographic Details
Main Authors: Christian Milani, Giulia Alessandri, Marta Mangifesta, Leonardo Mancabelli, Gabriele Andrea Lugli, Federico Fontana, Giulia Longhi, Rosaria Anzalone, Alice Viappiani, Sabrina Duranti, Francesca Turroni, Renato Costi, Alfredo Annicchiarico, Andrea Morini, Leopoldo Sarli, Maria Cristina Ossiprandi, Douwe van Sinderen, Marco Ventura
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSystems
Subjects:
metagenomics
ITS
profiling
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00404-20

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