Restoration of Hepatic and Intestinal Integrity by <i>Phyllanthus amarus</i> Is Dependent on Bax/Caspase 3 Modulation in Intestinal Ischemia-/Reperfusion-Induced Injury

Restoration of Hepatic and Intestinal Integrity by <i>Phyllanthus amarus</i> Is Dependent on Bax/Caspase 3 Modulation in Intestinal Ischemia-/Reperfusion-Induced Injury

Ethnopharmacological relevance: Oxidative stress is a key player in intestinal ischemia/reperfusion (I/R) injury (IIRI) with a tendency to trigger systemic inflammatory response, resulting in progressive distal organ injury. To date, the role of Bax/caspase 3 signaling in IIRI has not been reported....

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Bibliographic Details
Main Authors: Ayobami Oladele Afolabi, Tunmise Maryanne Akhigbe, Adeyemi Fatai Odetayo, Davinson Chuka Anyogu, Moses Agbomhere Hamed, Roland Eghoghosoa Akhigbe
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
<i>Phyllanthus amarus</i>
ischemia/reperfusion
oxidative stress
inflammation
apoptosis
hepatic function
Online Access:https://www.mdpi.com/1420-3049/27/16/5073

Internet

https://www.mdpi.com/1420-3049/27/16/5073

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