METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells

Abstract Rituximab has been incorporated into the standard treatment regimen for diffuse large B-cell lymphoma (DLBCL), and induces the death of tumor cells via complement-dependent cytotoxicity (CDC). Unfortunately, the resistance of DLBCL cells to Rituximab limits its clinical usefulness. It remai...

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Bibliographic Details
Main Authors: Junping Li, Zhigang Zhu, Yuan Zhu, Jinqing Li, Kangbao Li, Weijie Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01698-2

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