Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens
Borreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Thrombosis of the portal vein represents a significant problem too...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2018-11-01
|
| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/32910/pdf |
| _version_ | 1818998344694890496 |
|---|---|
| author | E V Reznik M P Prushkovskaya E D Presnova N A Novikova R A Ivaschenko E I Dedov A E Nikitin I G Nikitin |
| author_facet | E V Reznik M P Prushkovskaya E D Presnova N A Novikova R A Ivaschenko E I Dedov A E Nikitin I G Nikitin |
| author_sort | E V Reznik |
| collection | DOAJ |
| description | Borreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Thrombosis of the portal vein represents a significant problem too with high morbidity and mortality. The risk factors for splanchnic vein thrombosis include infections, but its relationship with borreliosis has not been studied. А 34-year-old man with chronic helicobacter-associated gastritis and gallstones was hospitalized due to development during the last 11 days of epigastric pain and fever to 38.7 °C after a picnic at the forest without a registered tick bite. The blood leukocytes were increased to 11.2*109/l, lymphocytes 70%, C-reactive protein 34.6 mg/l, procalcitonin 0.195 ng/ml. The multispiral computed tomography of the abdominal cavity revealed thrombosis of portal, lienalis and superior mesenteric veins. D-dimer was 1.98 mcg/ml, antithrombin III 75%. JACK2V617F, oncological, rheumatic, thrombophilia markers, blood and urine cultures were negative. A high concentration of anti-Borrelia burgdorferi IgM 62.2 U/ml and its increasing to 190 U/ml in dynamics was revealed at the immunofluorescence assay. Anti-Borrelia IgM to OspA, p31 and OspC, p25 were detected at the immunoblotting assay. Anticoagulation, doxycycline, detoxification therapy reduced pain and normalized temperature and inflammation markers. Vein thrombosis was not detected at the control tomography after 2 weeks. Despite that the combination of thrombosis and borreliosis is rare, it is necessary to screen for Borrelia antigens in patients with splanchnic vein thrombosis and fever. |
| first_indexed | 2024-12-20T22:00:02Z |
| format | Article |
| id | doaj.art-d4ea2e7dc7594a1ca8de4f2569db0819 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-20T22:00:02Z |
| publishDate | 2018-11-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-d4ea2e7dc7594a1ca8de4f2569db08192022-12-21T19:25:22Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422018-11-019011798910.26442/terarkh201890114-8929661Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigensE V Reznik0M P Prushkovskaya1E D Presnova2N A Novikova3R A Ivaschenko4E I Dedov5A E Nikitin6I G Nikitin7N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation; V.M. Buyanov City Clinical HospitalCentral Clinical HospitalN.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationCentral Clinical HospitalV.M. Buyanov City Clinical HospitalN.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation; Central Clinical HospitalCentral Clinical HospitalN.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationBorreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Thrombosis of the portal vein represents a significant problem too with high morbidity and mortality. The risk factors for splanchnic vein thrombosis include infections, but its relationship with borreliosis has not been studied. А 34-year-old man with chronic helicobacter-associated gastritis and gallstones was hospitalized due to development during the last 11 days of epigastric pain and fever to 38.7 °C after a picnic at the forest without a registered tick bite. The blood leukocytes were increased to 11.2*109/l, lymphocytes 70%, C-reactive protein 34.6 mg/l, procalcitonin 0.195 ng/ml. The multispiral computed tomography of the abdominal cavity revealed thrombosis of portal, lienalis and superior mesenteric veins. D-dimer was 1.98 mcg/ml, antithrombin III 75%. JACK2V617F, oncological, rheumatic, thrombophilia markers, blood and urine cultures were negative. A high concentration of anti-Borrelia burgdorferi IgM 62.2 U/ml and its increasing to 190 U/ml in dynamics was revealed at the immunofluorescence assay. Anti-Borrelia IgM to OspA, p31 and OspC, p25 were detected at the immunoblotting assay. Anticoagulation, doxycycline, detoxification therapy reduced pain and normalized temperature and inflammation markers. Vein thrombosis was not detected at the control tomography after 2 weeks. Despite that the combination of thrombosis and borreliosis is rare, it is necessary to screen for Borrelia antigens in patients with splanchnic vein thrombosis and fever.https://ter-arkhiv.ru/0040-3660/article/viewFile/32910/pdfborrelia burgdorferyborreliosislyme diseasethrombosisborrelia burgdorferyneuroborreliosis |
| spellingShingle | E V Reznik M P Prushkovskaya E D Presnova N A Novikova R A Ivaschenko E I Dedov A E Nikitin I G Nikitin Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens Терапевтический архив borrelia burgdorfery borreliosis lyme disease thrombosis borrelia burgdorfery neuroborreliosis |
| title | Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens |
| title_full | Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens |
| title_fullStr | Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens |
| title_full_unstemmed | Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens |
| title_short | Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens |
| title_sort | case of thrombosis of the portal vein and its branches in a patient seropositive for borrelia antigens |
| topic | borrelia burgdorfery borreliosis lyme disease thrombosis borrelia burgdorfery neuroborreliosis |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/32910/pdf |
| work_keys_str_mv | AT evreznik caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT mpprushkovskaya caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT edpresnova caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT nanovikova caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT raivaschenko caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT eidedov caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT aenikitin caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens AT ignikitin caseofthrombosisoftheportalveinanditsbranchesinapatientseropositiveforborreliaantigens |