Revealing within-species diversity in uncultured human gut bacteria with single-cell long-read sequencing

Revealing within-species diversity in uncultured human gut bacteria with single-cell long-read sequencing

Obtaining complete and accurate bacterial genomes is vital for studying the characteristics of uncultured bacteria. Single-cell genomics is a promising approach for the culture-independent recovery of bacterial genomes from individual cells. However, single-amplified genomes (SAGs) often have fragme...

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Bibliographic Details
Main Authors: Masato Kogawa, Yohei Nishikawa, Tatsuya Saeki, Takuya Yoda, Koji Arikawa, Haruko Takeyama, Masahito Hosokawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Microbiology
Subjects:
gut
microbiome
single-cell genomics
long-read sequencing
genome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1133917/full

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