A Platform Integrating Biophysical and Biochemical Stimuli to Enhance Differentiation and Maturation of Cardiomyocyte Subtypes Derived from Human Induced Pluripotent Stem Cells

A Platform Integrating Biophysical and Biochemical Stimuli to Enhance Differentiation and Maturation of Cardiomyocyte Subtypes Derived from Human Induced Pluripotent Stem Cells

To enhance the differentiation and maturation of cardiomyocytes derived from human induced pluripotent stem cells, we developed a bioreactor system that simultaneously imposes biophysical and biochemical stimuli on these committed cardiomyocytes. The cells were cultured within biohydrogels composed...

Full description

Bibliographic Details
Main Authors: Zhonggang Feng, Kota Sawada, Iori Ando, Riku Yoshinari, Daisuke Sato, Tadashi Kosawada
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
bioreactor
mechano-electrical stimulation
cardiac differentiation
cardiomyocyte subtypes
three-dimensional culture
ventricular extracellular matrix
Online Access:https://www.mdpi.com/2308-3425/12/2/56

Internet

https://www.mdpi.com/2308-3425/12/2/56

Similar Items