Dietary sucrose defines lifespan and metabolism in Drosophila
Nutrition affects various life-history traits. We used fruit flies Drosophila melanogaster to determine whether life-history traits, particularly life span and metabolism, are affected by dietary sucrose content. We fed flies by four different diets containing constant yeast concentration and increa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2020-10-01
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| Series: | The Ukrainian Biochemical Journal |
| Subjects: | |
| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Strilbytska_5_20.pdf |
| _version_ | 1797668865050673152 |
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| author | O. Strilbytska T. Strutynska U. Semaniuk N. Burdyliyk O. Lushchak |
| author_facet | O. Strilbytska T. Strutynska U. Semaniuk N. Burdyliyk O. Lushchak |
| author_sort | O. Strilbytska |
| collection | DOAJ |
| description | Nutrition affects various life-history traits. We used fruit flies Drosophila melanogaster to determine whether life-history traits, particularly life span and metabolism, are affected by dietary sucrose content. We fed flies by four different diets containing constant yeast concentration and increasing amounts of sugar ranged from 1% to 20%. We found that low sucrose diet increases female lifespan. We also showed, that low dietary sucrose maximized malate dehydrogenase, aspartate aminotransferase activity in males and lactate dehydrogenase activity in females. In addition, dietary carbohydrate has a considerable impact on urea level, suggesting that dietary carbohydrate impacts overall metabolism. Our findings reveal the influence of dietary sugar on metabolic enzymes activities, indicating an existence of optimal nutritional conditions for prolongevity phenotype and confirming an important impact of dietary sugar on life-history traits. |
| first_indexed | 2024-03-11T20:34:44Z |
| format | Article |
| id | doaj.art-d4eea6fc263a4f51b78dbaaf2962692f |
| institution | Directory Open Access Journal |
| issn | 2409-4943 2413-5003 |
| language | English |
| last_indexed | 2024-03-11T20:34:44Z |
| publishDate | 2020-10-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | The Ukrainian Biochemical Journal |
| spelling | doaj.art-d4eea6fc263a4f51b78dbaaf2962692f2023-10-02T07:19:17ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryThe Ukrainian Biochemical Journal2409-49432413-50032020-10-019259710510.15407/ubj92.05.097Dietary sucrose defines lifespan and metabolism in DrosophilaO. Strilbytska0T. Strutynska1U. Semaniuk2https://orcid.org/0000-0001-9837-3769N. Burdyliyk3O. Lushchak4https://orcid.org/0000-0002-4627-1987Vasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, UkraineVasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, UkraineVasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, UkraineVasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, UkraineVasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, UkraineNutrition affects various life-history traits. We used fruit flies Drosophila melanogaster to determine whether life-history traits, particularly life span and metabolism, are affected by dietary sucrose content. We fed flies by four different diets containing constant yeast concentration and increasing amounts of sugar ranged from 1% to 20%. We found that low sucrose diet increases female lifespan. We also showed, that low dietary sucrose maximized malate dehydrogenase, aspartate aminotransferase activity in males and lactate dehydrogenase activity in females. In addition, dietary carbohydrate has a considerable impact on urea level, suggesting that dietary carbohydrate impacts overall metabolism. Our findings reveal the influence of dietary sugar on metabolic enzymes activities, indicating an existence of optimal nutritional conditions for prolongevity phenotype and confirming an important impact of dietary sugar on life-history traits.http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Strilbytska_5_20.pdfnutritiondietcarbohydratelifespanmetabolismfruit fly drosophila |
| spellingShingle | O. Strilbytska T. Strutynska U. Semaniuk N. Burdyliyk O. Lushchak Dietary sucrose defines lifespan and metabolism in Drosophila The Ukrainian Biochemical Journal nutrition diet carbohydrate lifespan metabolism fruit fly drosophila |
| title | Dietary sucrose defines lifespan and metabolism in Drosophila |
| title_full | Dietary sucrose defines lifespan and metabolism in Drosophila |
| title_fullStr | Dietary sucrose defines lifespan and metabolism in Drosophila |
| title_full_unstemmed | Dietary sucrose defines lifespan and metabolism in Drosophila |
| title_short | Dietary sucrose defines lifespan and metabolism in Drosophila |
| title_sort | dietary sucrose defines lifespan and metabolism in drosophila |
| topic | nutrition diet carbohydrate lifespan metabolism fruit fly drosophila |
| url | http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Strilbytska_5_20.pdf |
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