Effect of leukapheresis on pain reduction in leukemic priapism
Priapism is a rare presentation of Chronic Myeloid Leukaemia (CML). It is also considered a medical emergency as delay in treatment may lead to impotence. Prompt medical and surgical interventions such as hydroxyurea, analgesia, phenylephrine injection and aspiration, open surgical shunting, and loc...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Asian Journal of Transfusion Science |
| Subjects: | |
| Online Access: | http://www.ajts.org/article.asp?issn=0973-6247;year=2022;volume=16;issue=1;spage=124;epage=127;aulast=Noushad |
| _version_ | 1828291308052021248 |
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| author | Shahida Noushad Dibyajyoti Sahoo Abhishekh Basavarajegowda Esha Toora Purshotam Paudel |
| author_facet | Shahida Noushad Dibyajyoti Sahoo Abhishekh Basavarajegowda Esha Toora Purshotam Paudel |
| author_sort | Shahida Noushad |
| collection | DOAJ |
| description | Priapism is a rare presentation of Chronic Myeloid Leukaemia (CML). It is also considered a medical emergency as delay in treatment may lead to impotence. Prompt medical and surgical interventions such as hydroxyurea, analgesia, phenylephrine injection and aspiration, open surgical shunting, and local radiation therapy are essential. Leukapheresis effectively reduces leukocyte count rapidly and effectively, thereby an important therapy along with other standard of care in CML-induced priapism. In the present case, priapism was the presenting symptom of CML. The same was managed with various modalities such as hydroxyurea, allopurinol, antibiotics, analgesics, sedatives, phenylephrine injection, and aspiration but failed to reduce priapism pain. With a single cycle of leukapheresis, priapism pain could be reduced significantly. |
| first_indexed | 2024-04-13T10:50:36Z |
| format | Article |
| id | doaj.art-d4f1e40deadf42a8886d2553fc3f3e8e |
| institution | Directory Open Access Journal |
| issn | 0973-6247 1998-3565 |
| language | English |
| last_indexed | 2024-04-13T10:50:36Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Transfusion Science |
| spelling | doaj.art-d4f1e40deadf42a8886d2553fc3f3e8e2022-12-22T02:49:40ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652022-01-0116112412710.4103/ajts.ajts_160_21Effect of leukapheresis on pain reduction in leukemic priapismShahida NoushadDibyajyoti SahooAbhishekh BasavarajegowdaEsha TooraPurshotam PaudelPriapism is a rare presentation of Chronic Myeloid Leukaemia (CML). It is also considered a medical emergency as delay in treatment may lead to impotence. Prompt medical and surgical interventions such as hydroxyurea, analgesia, phenylephrine injection and aspiration, open surgical shunting, and local radiation therapy are essential. Leukapheresis effectively reduces leukocyte count rapidly and effectively, thereby an important therapy along with other standard of care in CML-induced priapism. In the present case, priapism was the presenting symptom of CML. The same was managed with various modalities such as hydroxyurea, allopurinol, antibiotics, analgesics, sedatives, phenylephrine injection, and aspiration but failed to reduce priapism pain. With a single cycle of leukapheresis, priapism pain could be reduced significantly.http://www.ajts.org/article.asp?issn=0973-6247;year=2022;volume=16;issue=1;spage=124;epage=127;aulast=Noushadleukapheresispainpriapism |
| spellingShingle | Shahida Noushad Dibyajyoti Sahoo Abhishekh Basavarajegowda Esha Toora Purshotam Paudel Effect of leukapheresis on pain reduction in leukemic priapism Asian Journal of Transfusion Science leukapheresis pain priapism |
| title | Effect of leukapheresis on pain reduction in leukemic priapism |
| title_full | Effect of leukapheresis on pain reduction in leukemic priapism |
| title_fullStr | Effect of leukapheresis on pain reduction in leukemic priapism |
| title_full_unstemmed | Effect of leukapheresis on pain reduction in leukemic priapism |
| title_short | Effect of leukapheresis on pain reduction in leukemic priapism |
| title_sort | effect of leukapheresis on pain reduction in leukemic priapism |
| topic | leukapheresis pain priapism |
| url | http://www.ajts.org/article.asp?issn=0973-6247;year=2022;volume=16;issue=1;spage=124;epage=127;aulast=Noushad |
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