Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy

Introduction Chronic pelvic pain syndrome occurs in 4–14% of women. Pain pathomechanism in this syndrome is complex, as it is common to observe the features of nociceptive, inflammatory, neuropathic and psychogenic pain. The common findings in women with pelvic pain are endometriosis and pelvic adhe...

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Main Authors: Małgorzata Malec-Milewska, Bartosz Horosz, Agnieszka Sękowska, Iwona Kolęda, Dariusz Kosson, Grzegorz Jakiel
Format: Article
Language:English
Published: Institute of Rural Health 2015-05-01
Series:Annals of Agricultural and Environmental Medicine
Subjects:
Online Access:http://www.journalssystem.com/aaem/Pharmacological-treatment-and-regional-anesthesia-techniques-for-pain-management,72289,0,2.html
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author Małgorzata Malec-Milewska
Bartosz Horosz
Agnieszka Sękowska
Iwona Kolęda
Dariusz Kosson
Grzegorz Jakiel
author_facet Małgorzata Malec-Milewska
Bartosz Horosz
Agnieszka Sękowska
Iwona Kolęda
Dariusz Kosson
Grzegorz Jakiel
author_sort Małgorzata Malec-Milewska
collection DOAJ
description Introduction Chronic pelvic pain syndrome occurs in 4–14% of women. Pain pathomechanism in this syndrome is complex, as it is common to observe the features of nociceptive, inflammatory, neuropathic and psychogenic pain. The common findings in women with pelvic pain are endometriosis and pelvic adhesions. Objective Aim of the study was to test the effectiveness of pharmacological treatment and regional anesthesia techniques for pain control as the next step of treatment after the lack of clinical results of surgical and pharmacological methods normally used in the management of endometriosis and pelvic adhesions. Material and Methods 18 women were treated between January 2010 – October 2013 in the Pain Clinic of the Department of Anaesthesiology and Intensive Care at the Centre for Postgraduate Education in Warsaw due to chronic pelvic pain syndrome related to either endometriosis or pelvic adhesions. During the previous step of management, both conservative and surgical treatments were completed without achieving satisfactory results. Initial constant pain severity was 3–9 points on the Numeric Rating Scale, while the reported paroxysmal pain level was 7–10. The pharmacological treatment implemented was based on oral gabapentinoids and antidepressants, aided by neurolytic block of ganglion of Walther, pudendal nerve blocks and topical treatment (5% lidocaine, 10% amitriptyline, 10% gabapentin). Results In 17 women, a significant reduction of both constant and paroxysmal pain was achieved, of which complete and permanent cessation of pain occurred in 6 cases. One patient experienced no improvement in the severity of her symptoms. Conclusions The combination of pain management with pharmacological treatment, pudendal nerve blocks, neurolysis of ganglion impar (Walther) and topical preparations in cases of chronic pelvic pain syndrome seems to be adequate medical conduct after failed or otherwise ineffective causative therapy.
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spelling doaj.art-d4f1e705c1ee4ad5b225981ea89b8d642022-12-21T22:28:37ZengInstitute of Rural HealthAnnals of Agricultural and Environmental Medicine1232-19661898-22632015-05-0122235335610.5604/12321966.115209472289Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategyMałgorzata Malec-Milewska0Bartosz Horosz1Agnieszka Sękowska2Iwona Kolęda3Dariusz Kosson4Grzegorz Jakiel5Pain Clinic, Department of Anaesthesiology and Intensive Care, Medical Centre for Postgraduate Education, Warsaw, PolandPain Clinic, Department of Anaesthesiology and Intensive Care, Medical Centre for Postgraduate Education, Warsaw, PolandPain Clinic, Department of Anaesthesiology and Intensive Care, Medical Centre for Postgraduate Education, Warsaw, PolandPain Clinic, Department of Anaesthesiology and Intensive Care, Medical Centre for Postgraduate Education, Warsaw, PolandPain Clinic, Department of Anaesthesiology and Intensive Care, Medical Centre for Postgraduate Education, Warsaw, Poland1 st Department of Obstetrics and Gynaecology, Medical Centre for Postgraduate Education, Warsaw, PolandIntroduction Chronic pelvic pain syndrome occurs in 4–14% of women. Pain pathomechanism in this syndrome is complex, as it is common to observe the features of nociceptive, inflammatory, neuropathic and psychogenic pain. The common findings in women with pelvic pain are endometriosis and pelvic adhesions. Objective Aim of the study was to test the effectiveness of pharmacological treatment and regional anesthesia techniques for pain control as the next step of treatment after the lack of clinical results of surgical and pharmacological methods normally used in the management of endometriosis and pelvic adhesions. Material and Methods 18 women were treated between January 2010 – October 2013 in the Pain Clinic of the Department of Anaesthesiology and Intensive Care at the Centre for Postgraduate Education in Warsaw due to chronic pelvic pain syndrome related to either endometriosis or pelvic adhesions. During the previous step of management, both conservative and surgical treatments were completed without achieving satisfactory results. Initial constant pain severity was 3–9 points on the Numeric Rating Scale, while the reported paroxysmal pain level was 7–10. The pharmacological treatment implemented was based on oral gabapentinoids and antidepressants, aided by neurolytic block of ganglion of Walther, pudendal nerve blocks and topical treatment (5% lidocaine, 10% amitriptyline, 10% gabapentin). Results In 17 women, a significant reduction of both constant and paroxysmal pain was achieved, of which complete and permanent cessation of pain occurred in 6 cases. One patient experienced no improvement in the severity of her symptoms. Conclusions The combination of pain management with pharmacological treatment, pudendal nerve blocks, neurolysis of ganglion impar (Walther) and topical preparations in cases of chronic pelvic pain syndrome seems to be adequate medical conduct after failed or otherwise ineffective causative therapy.http://www.journalssystem.com/aaem/Pharmacological-treatment-and-regional-anesthesia-techniques-for-pain-management,72289,0,2.htmlchronic pelvic pain syndromeendometriosispelvic adhesionsamitriptylinegabapentinpudendal nerve blockganglion of Walther
spellingShingle Małgorzata Malec-Milewska
Bartosz Horosz
Agnieszka Sękowska
Iwona Kolęda
Dariusz Kosson
Grzegorz Jakiel
Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
Annals of Agricultural and Environmental Medicine
chronic pelvic pain syndrome
endometriosis
pelvic adhesions
amitriptyline
gabapentin
pudendal nerve block
ganglion of Walther
title Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
title_full Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
title_fullStr Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
title_full_unstemmed Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
title_short Pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
title_sort pharmacological treatment and regional anesthesia techniques for pain management after completion of both conservative and surgical treatment of endometriosis and pelvic adhesions in women with chronic pelvic pain as a mandated treatment strategy
topic chronic pelvic pain syndrome
endometriosis
pelvic adhesions
amitriptyline
gabapentin
pudendal nerve block
ganglion of Walther
url http://www.journalssystem.com/aaem/Pharmacological-treatment-and-regional-anesthesia-techniques-for-pain-management,72289,0,2.html
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