Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast Cancer

Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast Cancer

Circulating tumor cells (CTCs) belong to a heterogeneous pool of rare cells, and a unequivocal phenotypic definition of CTC is lacking. Here, we present a definition of metabolically-altered CTC (MBA-CTCs) as CD45-negative cells with an increased extracellular acidification rate, detected with a sin...

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Bibliographic Details
Main Authors: Giulia Brisotto, Eva Biscontin, Elisabetta Rossi, Michela Bulfoni, Aigars Piruska, Simon Spazzapan, Cristina Poggiana, Riccardo Vidotto, Agostino Steffan, Alfonso Colombatti, Wilhelm T. S. Huck, Daniela Cesselli, Rita Zamarchi, Matteo Turetta, Fabio Del Ben
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
breast cancer
circulating tumor cells
liquid biopsy
metabolism
droplet microfluidics
pH
Online Access:https://www.mdpi.com/2072-6694/12/4/1005

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