Difference in PaO2/FiO2 between high-flow nasal cannula and Venturi mask in hypoxemic COVID-19 patients

Difference in PaO2/FiO2 between high-flow nasal cannula and Venturi mask in hypoxemic COVID-19 patients

Abstract The ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO2/FiO2) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. In these patients, the assessment of the true FiO2 in the inspired mixture may b...

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Bibliographic Details
Main Authors: Ilenia Gatto, Emanuela Biagioni, Irene Coloretti, Serena Viappiani, Stefano Busani, Massimo Girardis
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Anesthesia, Analgesia and Critical Care
Subjects:
COVID-19
ICU
HFNC
PaO2/FiO2
Online Access:https://doi.org/10.1186/s44158-022-00051-w
Description
Summary:Abstract The ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO2/FiO2) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. In these patients, the assessment of the true FiO2 in the inspired mixture may be difficult with consequent inaccuracies in PaO2/FiO2 assessment. In 30 severe COVID-19 patients, we observed that PaO2/FiO2 values measured immediately before and after the transition from high-flow nasal cannula (HFNC) to one commercially available Venturi mask O2 therapy were similar (bias mean value 0, standard deviation 23 mmHg). In COVID-19 patients recovering from respiratory failure, PaO2/FiO2 is not different whether measured with a commercially available Venturi mask or HFNC.
ISSN:2731-3786

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