Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry
Angiosarcomas of oral cavity and salivary gland represent 1% of all cases reported in the literature and are therefore considered as extremely rare. To the best of our knowledge very few cases of angiosarcomas involving mandibular gingiva have been reported previously. Here, we report a case of an...
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| Language: | English |
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JCDR Research and Publications Private Limited
2016-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8080/18497_CE(Ra1)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
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| author | Santosh Hunasgi Anila Koneru M. Vanishree Vardendra Manvikar |
| author_facet | Santosh Hunasgi Anila Koneru M. Vanishree Vardendra Manvikar |
| author_sort | Santosh Hunasgi |
| collection | DOAJ |
| description | Angiosarcomas of oral cavity and salivary gland represent 1% of all cases reported in the literature and are therefore considered as
extremely rare. To the best of our knowledge very few cases of angiosarcomas involving mandibular gingiva have been reported previously.
Here, we report a case of angiosarcoma occurring in the gingiva with review of literature on clinical features. A 30-year-old female patient
presented with a complaint of a small growing mass in relation to lower front teeth. Intraoral examination revealed a soft sessile growth
arising from the labial gingiva in relation to 31 and 41 on the labial aspect extending distally to 32. The lesion was locally excised.
Histolopathological analysis showed that the tumour was composed of spindle shaped to polygonal cells with hyperchromatic nuclei,
conspicuous nucleoli and intracytoplasmic vacuoles, mitotic figure were also scattered. Immunohistochemical staining revealed that the
tumour cells was positive for factor VIII-related antigen, CD31 and CD34. An excisional biopsy showed a diagnosis of angiosarcoma.
After two months patient reported back with the same chief complaint. This present case is a 17th case report of angiosarcoma arising
in anterior mandiblular gingiva. |
| first_indexed | 2024-12-11T17:59:19Z |
| format | Article |
| id | doaj.art-d4f6da12548a4b36a5d435720b49dda0 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T17:59:19Z |
| publishDate | 2016-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-d4f6da12548a4b36a5d435720b49dda02022-12-22T00:55:58ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-07-01107ZD01ZD0410.7860/JCDR/2016/18497.8080Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with ImmunohistochemistrySantosh Hunasgi0Anila Koneru1M. Vanishree2Vardendra Manvikar3Professor, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital, Raichur, Karnataka, India.Reader, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital, Raichur, Karnataka, India.Professor and Head, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital, Raichur, Karnataka, India.Assistant Professor, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital, Raichur, Karnataka, India.Angiosarcomas of oral cavity and salivary gland represent 1% of all cases reported in the literature and are therefore considered as extremely rare. To the best of our knowledge very few cases of angiosarcomas involving mandibular gingiva have been reported previously. Here, we report a case of angiosarcoma occurring in the gingiva with review of literature on clinical features. A 30-year-old female patient presented with a complaint of a small growing mass in relation to lower front teeth. Intraoral examination revealed a soft sessile growth arising from the labial gingiva in relation to 31 and 41 on the labial aspect extending distally to 32. The lesion was locally excised. Histolopathological analysis showed that the tumour was composed of spindle shaped to polygonal cells with hyperchromatic nuclei, conspicuous nucleoli and intracytoplasmic vacuoles, mitotic figure were also scattered. Immunohistochemical staining revealed that the tumour cells was positive for factor VIII-related antigen, CD31 and CD34. An excisional biopsy showed a diagnosis of angiosarcoma. After two months patient reported back with the same chief complaint. This present case is a 17th case report of angiosarcoma arising in anterior mandiblular gingiva.https://jcdr.net/articles/PDF/8080/18497_CE(Ra1)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdfcd31cd34factor viii-related antigengingivamalignant vascular tumourmandible |
| spellingShingle | Santosh Hunasgi Anila Koneru M. Vanishree Vardendra Manvikar Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry Journal of Clinical and Diagnostic Research cd31 cd34 factor viii-related antigen gingiva malignant vascular tumour mandible |
| title | Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry |
| title_full | Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry |
| title_fullStr | Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry |
| title_full_unstemmed | Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry |
| title_short | Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence – A Case Report with Immunohistochemistry |
| title_sort | angiosarcoma of anterior mandibular gingiva showing recurrence a case report with immunohistochemistry |
| topic | cd31 cd34 factor viii-related antigen gingiva malignant vascular tumour mandible |
| url | https://jcdr.net/articles/PDF/8080/18497_CE(Ra1)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
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