Multivariate analysis of corneal endothelial cell count reduction after cataract surgery

AIM:To investigate the factors related to the decrease of corneal endothelial cell number after phacoemulsification in cataract patients. <p>METHODS: We selected 98 patients(120 eyes)in Ophthalmic Center from July 2014 to July 2016 underwent phacoemulsification and they were retrospectively an...

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Main Authors: Duan-Rong Cao, Jing-Qing Gong, Ling Jin, Jing-Yi Niu, Yu-Ling Niu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-04-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2018/4/201804031.pdf
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author Duan-Rong Cao
Jing-Qing Gong
Ling Jin
Jing-Yi Niu
Yu-Ling Niu
author_facet Duan-Rong Cao
Jing-Qing Gong
Ling Jin
Jing-Yi Niu
Yu-Ling Niu
author_sort Duan-Rong Cao
collection DOAJ
description AIM:To investigate the factors related to the decrease of corneal endothelial cell number after phacoemulsification in cataract patients. <p>METHODS: We selected 98 patients(120 eyes)in Ophthalmic Center from July 2014 to July 2016 underwent phacoemulsification and they were retrospectively analyzed. According to the central corneal endothelial cell density before and 2mo after the operation, they were divided into serious loss group of 52 cases(67 eyes, density of central corneal endothelial cells loss rate no less than 12.3%), the general loss group of 46 cases(53 eyes, the density of central corneal endothelial cell loss rate <12.3%). Relevant indicators of general information, operation of the two groups were compared, the influence factors of non conditional Logistic regression analysis method was used to investigate the effect for corneal endothelial cell loss in cataract patients. <p>RESULTS: Serious loss group and the general group on gender, rate with hypertension, rate with diabetes, rate with high blood lipids, with shallow anterior chamber, corneal diameter and suction time comparison, had no statistically significant differences(<i>P</i>>0.05). Nuclear hardness classification of Emery lens, ultrasonic power, ultrasonic emulsification time, age between groups were significantly different(<i>P</i><0.05). By using Logistic analysis method, the results showed that increased Emery lens nucleus grading, ultrasonic energy, phacoemulsification time, age were independent risk factors for corneal endothelial cells after phacoemulsification(<i>P</i><0.05). <p>CONCLUSION: The main factors that influence the decrease of corneal endothelial cell number after phacoemulsification are Emery lens, higher grade of nucleus of lens, increase of ultrasonic energy, longer time of phacoemulsification and increased age.
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spelling doaj.art-d4f835287bcb42b98d3d9493a23d89b02022-12-22T02:58:28ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-04-0118471671910.3980/j.issn.1672-5123.2018.4.31Multivariate analysis of corneal endothelial cell count reduction after cataract surgeryDuan-Rong Cao0Jing-Qing Gong1Ling Jin2Jing-Yi Niu3Yu-Ling Niu4Department of Ophthalmology, Bao'an District People's Hospital, Shenzhen 518101,Guangdong Province, ChinaDepartment of Ophthalmology, Bao'an District People's Hospital, Shenzhen 518101,Guangdong Province, ChinaDepartment of Ophthalmology, Bao'an District People's Hospital, Shenzhen 518101,Guangdong Province, ChinaDepartment of Ophthalmology, Bao'an District People's Hospital, Shenzhen 518101,Guangdong Province, ChinaDepartment of Ophthalmology, Bao'an District People's Hospital, Shenzhen 518101,Guangdong Province, ChinaAIM:To investigate the factors related to the decrease of corneal endothelial cell number after phacoemulsification in cataract patients. <p>METHODS: We selected 98 patients(120 eyes)in Ophthalmic Center from July 2014 to July 2016 underwent phacoemulsification and they were retrospectively analyzed. According to the central corneal endothelial cell density before and 2mo after the operation, they were divided into serious loss group of 52 cases(67 eyes, density of central corneal endothelial cells loss rate no less than 12.3%), the general loss group of 46 cases(53 eyes, the density of central corneal endothelial cell loss rate <12.3%). Relevant indicators of general information, operation of the two groups were compared, the influence factors of non conditional Logistic regression analysis method was used to investigate the effect for corneal endothelial cell loss in cataract patients. <p>RESULTS: Serious loss group and the general group on gender, rate with hypertension, rate with diabetes, rate with high blood lipids, with shallow anterior chamber, corneal diameter and suction time comparison, had no statistically significant differences(<i>P</i>>0.05). Nuclear hardness classification of Emery lens, ultrasonic power, ultrasonic emulsification time, age between groups were significantly different(<i>P</i><0.05). By using Logistic analysis method, the results showed that increased Emery lens nucleus grading, ultrasonic energy, phacoemulsification time, age were independent risk factors for corneal endothelial cells after phacoemulsification(<i>P</i><0.05). <p>CONCLUSION: The main factors that influence the decrease of corneal endothelial cell number after phacoemulsification are Emery lens, higher grade of nucleus of lens, increase of ultrasonic energy, longer time of phacoemulsification and increased age.http://ies.ijo.cn/cn_publish/2018/4/201804031.pdfcataractphacoemulsificationcorneal endothelial cellsrelated factorsrelated factors
spellingShingle Duan-Rong Cao
Jing-Qing Gong
Ling Jin
Jing-Yi Niu
Yu-Ling Niu
Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
Guoji Yanke Zazhi
cataract
phacoemulsification
corneal endothelial cells
related factors
related factors
title Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
title_full Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
title_fullStr Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
title_full_unstemmed Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
title_short Multivariate analysis of corneal endothelial cell count reduction after cataract surgery
title_sort multivariate analysis of corneal endothelial cell count reduction after cataract surgery
topic cataract
phacoemulsification
corneal endothelial cells
related factors
related factors
url http://ies.ijo.cn/cn_publish/2018/4/201804031.pdf
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AT jingyiniu multivariateanalysisofcornealendothelialcellcountreductionaftercataractsurgery
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