Zebrafish WNK lysine deficient protein kinase 1 (wnk1) affects angiogenesis associated with VEGF signaling.

Zebrafish WNK lysine deficient protein kinase 1 (wnk1) affects angiogenesis associated with VEGF signaling.

The WNK1 (WNK lysine deficient protein kinase 1) protein is a serine/threonine protein kinase with emerging roles in cancer. WNK1 causes hypertension and hyperkalemia when overexpressed and cardiovascular defects when ablated in mice. In this study, the role of Wnk1 in angiogenesis was explored usin...

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Bibliographic Details
Main Authors: Ju-Geng Lai, Su-Mei Tsai, Hsiao-Chen Tu, Wen-Chuan Chen, Fong-Ji Kou, Jeng-Wei Lu, Horng-Dar Wang, Chou-Long Huang, Chiou-Hwa Yuh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149531?pdf=render

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