The status of refrigeration solutions for last mile vaccine delivery in low-income settings

Recommendations for storage of most vaccines imply a continuous exposure to a temperature range between 0 °C and 10 °C, from the production to the administration to beneficiaries. According to the World Health Organization, more than 50% of vaccines are wasted around the world. Discontinuities of th...

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Main Authors: Magali Cattin, Sashidhar Jonnalagedda, Solomzi Makohliso, Klaus Schönenberger
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Vaccine: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590136222000444
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author Magali Cattin
Sashidhar Jonnalagedda
Solomzi Makohliso
Klaus Schönenberger
author_facet Magali Cattin
Sashidhar Jonnalagedda
Solomzi Makohliso
Klaus Schönenberger
author_sort Magali Cattin
collection DOAJ
description Recommendations for storage of most vaccines imply a continuous exposure to a temperature range between 0 °C and 10 °C, from the production to the administration to beneficiaries. According to the World Health Organization, more than 50% of vaccines are wasted around the world. Discontinuities of the cold chain in low-income settings where electricity is scarce contributes to this wastage. Recently, several advances have been made in cooling technologies to store and transport vaccines. This paper presents an overview of refrigeration technologies based on scientific publications, industry white papers and other grey literature. With a focus on vaccine transport, we briefly describe each refrigeration method, its best performing available devices as well as the outstanding research challenges in order to further improve its performance.
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spelling doaj.art-d4ff9a0062d74805b71e0dbd17f830d32022-12-22T03:42:09ZengElsevierVaccine: X2590-13622022-08-0111100184The status of refrigeration solutions for last mile vaccine delivery in low-income settingsMagali Cattin0Sashidhar Jonnalagedda1Solomzi Makohliso2Klaus Schönenberger3EssentialTech Centre, Ecole Polytechnique Fédérale de Lausanne, Station 10, 1015 Lausanne, SwitzerlandEssentialTech Centre, Ecole Polytechnique Fédérale de Lausanne, Station 10, 1015 Lausanne, SwitzerlandEssentialTech Centre, Ecole Polytechnique Fédérale de Lausanne, Station 10, 1015 Lausanne, SwitzerlandCorresponding author.; EssentialTech Centre, Ecole Polytechnique Fédérale de Lausanne, Station 10, 1015 Lausanne, SwitzerlandRecommendations for storage of most vaccines imply a continuous exposure to a temperature range between 0 °C and 10 °C, from the production to the administration to beneficiaries. According to the World Health Organization, more than 50% of vaccines are wasted around the world. Discontinuities of the cold chain in low-income settings where electricity is scarce contributes to this wastage. Recently, several advances have been made in cooling technologies to store and transport vaccines. This paper presents an overview of refrigeration technologies based on scientific publications, industry white papers and other grey literature. With a focus on vaccine transport, we briefly describe each refrigeration method, its best performing available devices as well as the outstanding research challenges in order to further improve its performance.http://www.sciencedirect.com/science/article/pii/S2590136222000444Vaccine transportationCold chainOff-grid refrigerationLast mile delivery
spellingShingle Magali Cattin
Sashidhar Jonnalagedda
Solomzi Makohliso
Klaus Schönenberger
The status of refrigeration solutions for last mile vaccine delivery in low-income settings
Vaccine: X
Vaccine transportation
Cold chain
Off-grid refrigeration
Last mile delivery
title The status of refrigeration solutions for last mile vaccine delivery in low-income settings
title_full The status of refrigeration solutions for last mile vaccine delivery in low-income settings
title_fullStr The status of refrigeration solutions for last mile vaccine delivery in low-income settings
title_full_unstemmed The status of refrigeration solutions for last mile vaccine delivery in low-income settings
title_short The status of refrigeration solutions for last mile vaccine delivery in low-income settings
title_sort status of refrigeration solutions for last mile vaccine delivery in low income settings
topic Vaccine transportation
Cold chain
Off-grid refrigeration
Last mile delivery
url http://www.sciencedirect.com/science/article/pii/S2590136222000444
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