Lidocaine spray 10% prior to intravenous catheterisation in dogs

Abstract A common and to some degree painful procedure in veterinary practice is to insert an intra-venous catheter. In both human and veterinary medicine, a topical mixture of lidocaine and prilocaine (EMLA cream) has shown to reduce the pain, however a period of 60 min between application and init...

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Main Authors: Emma Hoeberg, Tonje Loken Kolstad, Liisa Martine Moller, Silje Kristine Rosvold, Maren Heggernes Softeland, Henning Andreas Haga, Andreas Lervik
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Acta Veterinaria Scandinavica
Subjects:
Online Access:https://doi.org/10.1186/s13028-022-00639-w
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author Emma Hoeberg
Tonje Loken Kolstad
Liisa Martine Moller
Silje Kristine Rosvold
Maren Heggernes Softeland
Henning Andreas Haga
Andreas Lervik
author_facet Emma Hoeberg
Tonje Loken Kolstad
Liisa Martine Moller
Silje Kristine Rosvold
Maren Heggernes Softeland
Henning Andreas Haga
Andreas Lervik
author_sort Emma Hoeberg
collection DOAJ
description Abstract A common and to some degree painful procedure in veterinary practice is to insert an intra-venous catheter. In both human and veterinary medicine, a topical mixture of lidocaine and prilocaine (EMLA cream) has shown to reduce the pain, however a period of 60 min between application and initiation of the procedure is recommended. This time lapse is not always suitable for clinical practise and a shorter time before anaesthetic effect is therefore desirable. Lidocaine has a shorter time lapse (1–3 min) when used on mucus membrane; however, the effect of lidocaine for desensitization of skin has shown variable results in humans. The aim of the study was to evaluate the effect of topical lidocaine spray 10% on the response to placement of venous catheters in dogs. Topical lidocaine spray 10% or NaCl 0.9% was administered prior to placing an intravenous catheter in the cephalic vein. A cross-over of treatment with 2 h wash out period was used before placing a catheter in the opposite cephalic vein. The procedure was video recorded and the dogs’ responses were later scored by three persons blinded to treatment using a visual analogue scale. The VAS scores were normalised and the mean difference between treatments were compared using Wilcox signed-rank test. This study could not find a statistical difference between the treatments (P = 0.1763) and could conclude that no significant difference in response to intravenous catheterisation was found between application of NaCl 0.9% or lidocaine 10% prior to the procedure.
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spelling doaj.art-d50356063d344c8ca4ac5cd5b3ddeb2a2022-12-22T02:34:47ZengBMCActa Veterinaria Scandinavica1751-01472022-08-016411410.1186/s13028-022-00639-wLidocaine spray 10% prior to intravenous catheterisation in dogsEmma Hoeberg0Tonje Loken Kolstad1Liisa Martine Moller2Silje Kristine Rosvold3Maren Heggernes Softeland4Henning Andreas Haga5Andreas Lervik6Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life SciencesAbstract A common and to some degree painful procedure in veterinary practice is to insert an intra-venous catheter. In both human and veterinary medicine, a topical mixture of lidocaine and prilocaine (EMLA cream) has shown to reduce the pain, however a period of 60 min between application and initiation of the procedure is recommended. This time lapse is not always suitable for clinical practise and a shorter time before anaesthetic effect is therefore desirable. Lidocaine has a shorter time lapse (1–3 min) when used on mucus membrane; however, the effect of lidocaine for desensitization of skin has shown variable results in humans. The aim of the study was to evaluate the effect of topical lidocaine spray 10% on the response to placement of venous catheters in dogs. Topical lidocaine spray 10% or NaCl 0.9% was administered prior to placing an intravenous catheter in the cephalic vein. A cross-over of treatment with 2 h wash out period was used before placing a catheter in the opposite cephalic vein. The procedure was video recorded and the dogs’ responses were later scored by three persons blinded to treatment using a visual analogue scale. The VAS scores were normalised and the mean difference between treatments were compared using Wilcox signed-rank test. This study could not find a statistical difference between the treatments (P = 0.1763) and could conclude that no significant difference in response to intravenous catheterisation was found between application of NaCl 0.9% or lidocaine 10% prior to the procedure.https://doi.org/10.1186/s13028-022-00639-wLocal anaestheticSkin desensitizationVisual analouge scale
spellingShingle Emma Hoeberg
Tonje Loken Kolstad
Liisa Martine Moller
Silje Kristine Rosvold
Maren Heggernes Softeland
Henning Andreas Haga
Andreas Lervik
Lidocaine spray 10% prior to intravenous catheterisation in dogs
Acta Veterinaria Scandinavica
Local anaesthetic
Skin desensitization
Visual analouge scale
title Lidocaine spray 10% prior to intravenous catheterisation in dogs
title_full Lidocaine spray 10% prior to intravenous catheterisation in dogs
title_fullStr Lidocaine spray 10% prior to intravenous catheterisation in dogs
title_full_unstemmed Lidocaine spray 10% prior to intravenous catheterisation in dogs
title_short Lidocaine spray 10% prior to intravenous catheterisation in dogs
title_sort lidocaine spray 10 prior to intravenous catheterisation in dogs
topic Local anaesthetic
Skin desensitization
Visual analouge scale
url https://doi.org/10.1186/s13028-022-00639-w
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