Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge

Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge

Background: In most countries, participation in colorectal cancer (CRC) screening programs with the immunological fecal occult blood test (iFOBT) is low. Mutations of RAS and BRAF occur early in colorectal carcinogenesis and “liquid biopsy” allows detection of mutated circulating tumor DNA (ctDNA)....

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Bibliographic Details
Main Authors: Audelaure Junca, Gaëlle Tachon, Camille Evrard, Claire Villalva, Eric Frouin, Lucie Karayan-Tapon, David Tougeron
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
circulating tumor DNA
liquid biopsy
droplet digital PCR
colorectal cancer
fecal occult blood test
Online Access:https://www.mdpi.com/2072-6694/12/6/1482

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