Self-association of human beta-galactocerebrosidase: Dependence on pH, salt, and surfactant.

Self-association of human beta-galactocerebrosidase: Dependence on pH, salt, and surfactant.

Krabbe disease, also known as globoid cell leukodystrophy, is a rare genetic neurodegenerative disease caused by a deficiency of the galactocerebrosidase enzyme. To understand the association status of human beta-galactocerebrosidase (hGALC) in solution, we employed analytical ultracentrifugation (A...

Full description

Bibliographic Details
Main Authors: Eunhee Lee, Nazila Salamat-Miller, Walter F Stafford, Katherine Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226618&type=printable

Similar Items

Similar Items