Incidence and risk factors for Retinopathy of pre maturity

Introduction: Retinopathy of prematurity (ROP) or retrolental fibroplasia as it was originally named,has had a most curious life span as a twentieth century disease.These out breaks of the disease occurred approximately 25 years apart in the mid 1950s and late 1970s. Retinopathy of prematurity is be...

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Main Author: Amith Kumar Ch1, Ch Sahay2, Mounika Krishna3, Sowmithra4
Format: Article
Language:English
Published: Prathima Institute of Medical Sciences 2017-04-01
Series:Perspectives In Medical Research
Subjects:
Online Access:http://www.pimr.org.in/amithch_ab_vol5-issue1.php
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author Amith Kumar Ch1, Ch Sahay2, Mounika Krishna3, Sowmithra4
author_facet Amith Kumar Ch1, Ch Sahay2, Mounika Krishna3, Sowmithra4
author_sort Amith Kumar Ch1, Ch Sahay2, Mounika Krishna3, Sowmithra4
collection DOAJ
description Introduction: Retinopathy of prematurity (ROP) or retrolental fibroplasia as it was originally named,has had a most curious life span as a twentieth century disease.These out breaks of the disease occurred approximately 25 years apart in the mid 1950s and late 1970s. Retinopathy of prematurity is becoming a major cause of potentially preventable blindness among children in middle income countries that have introduced neonatal intensive care units for preterm and low birth weight babies. Aims and Objective :So the present study helps to determine the incidence of retinopathy of prematurity in neonates and to determine its association with certain risk factors. Materials and Methods :It is a clinical study of all neonates with a gestational age less than 36 weeks and /or a birth weight of less than 2000gms at Prathima Institute of Medical Sciences,Karimnagar for a period 2years. Neonates were evaluated through detailed clinical history, detailed anterior segment examination and indirect ophthalmoscopy after full dilatation of pupils. Results :Of the 100 neonates screened, 53 were males (53 %) and 47 were females (47%). Among the neonates who developed ROP, 23 were males (51.11%) and 22 were females (48.88%). Incidence of ROP among male and female babies is nearly equal and no statistically significant correlation could be found.Of the 45 neonates who were found to have ROP, 13 neonates were in stage 1 (28.88%), 16 in stage 2 (35.55%), 13 in stage 3 (28.88%), 2 in stage 4 (4.44%) and 1 in APROP stage of the disease. 12 infants had plus 42.05%. Conclusion : The incidence of ROP in the present study was 42.05% for any stage of which 62.22% were in stage 1 or 2 of the disease. The incidence of ROP showed a significant statistical correalation with prematurity, low birth weight, RDS, supplemental oxygen, blood transfusion, and injection betamethasone to mother. Injection betamethasone to the mother has a significant protective effect on the development of ROP.
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spelling doaj.art-d5088bdfe4d64f9ab5d97867fd5a7b242023-11-24T11:52:42ZengPrathima Institute of Medical SciencesPerspectives In Medical Research2348-14472348-229X2017-04-01514649Incidence and risk factors for Retinopathy of pre maturityAmith Kumar Ch1, Ch Sahay2, Mounika Krishna3, Sowmithra40 Prathima Insitute of Medical SciencesIntroduction: Retinopathy of prematurity (ROP) or retrolental fibroplasia as it was originally named,has had a most curious life span as a twentieth century disease.These out breaks of the disease occurred approximately 25 years apart in the mid 1950s and late 1970s. Retinopathy of prematurity is becoming a major cause of potentially preventable blindness among children in middle income countries that have introduced neonatal intensive care units for preterm and low birth weight babies. Aims and Objective :So the present study helps to determine the incidence of retinopathy of prematurity in neonates and to determine its association with certain risk factors. Materials and Methods :It is a clinical study of all neonates with a gestational age less than 36 weeks and /or a birth weight of less than 2000gms at Prathima Institute of Medical Sciences,Karimnagar for a period 2years. Neonates were evaluated through detailed clinical history, detailed anterior segment examination and indirect ophthalmoscopy after full dilatation of pupils. Results :Of the 100 neonates screened, 53 were males (53 %) and 47 were females (47%). Among the neonates who developed ROP, 23 were males (51.11%) and 22 were females (48.88%). Incidence of ROP among male and female babies is nearly equal and no statistically significant correlation could be found.Of the 45 neonates who were found to have ROP, 13 neonates were in stage 1 (28.88%), 16 in stage 2 (35.55%), 13 in stage 3 (28.88%), 2 in stage 4 (4.44%) and 1 in APROP stage of the disease. 12 infants had plus 42.05%. Conclusion : The incidence of ROP in the present study was 42.05% for any stage of which 62.22% were in stage 1 or 2 of the disease. The incidence of ROP showed a significant statistical correalation with prematurity, low birth weight, RDS, supplemental oxygen, blood transfusion, and injection betamethasone to mother. Injection betamethasone to the mother has a significant protective effect on the development of ROP.http://www.pimr.org.in/amithch_ab_vol5-issue1.phpretinopathy of prematuritylow birthweightneonates
spellingShingle Amith Kumar Ch1, Ch Sahay2, Mounika Krishna3, Sowmithra4
Incidence and risk factors for Retinopathy of pre maturity
Perspectives In Medical Research
retinopathy of prematurity
low birthweight
neonates
title Incidence and risk factors for Retinopathy of pre maturity
title_full Incidence and risk factors for Retinopathy of pre maturity
title_fullStr Incidence and risk factors for Retinopathy of pre maturity
title_full_unstemmed Incidence and risk factors for Retinopathy of pre maturity
title_short Incidence and risk factors for Retinopathy of pre maturity
title_sort incidence and risk factors for retinopathy of pre maturity
topic retinopathy of prematurity
low birthweight
neonates
url http://www.pimr.org.in/amithch_ab_vol5-issue1.php
work_keys_str_mv AT amithkumarch1chsahay2mounikakrishna3sowmithra4 incidenceandriskfactorsforretinopathyofprematurity