Spectroscopic and Molecular Docking Studies of the in Vitro Interaction between Puerarin and Cytochrome P450

Spectroscopic and Molecular Docking Studies of the in Vitro Interaction between Puerarin and Cytochrome P450

Puerarin, an isoflavone glycoside extracted from Pueraria plants, has various medical functions. Cytochrome P450s (CYPs) are crucial phase I metabolizing enzymes, which have been spotlighted for their effects on drug metabolism. The interaction between puerarin and CYPs (CYP1A2 and CYP2D6) was inves...

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Bibliographic Details
Main Authors: Jiangjuan Shao, Jianwei Chen, Tingting Li, Xiaoli Zhao
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
puerarin
cytochrome P450
spectroscopy
molecular docking
Online Access:http://www.mdpi.com/1420-3049/19/4/4760

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