In-Silico Analysis of Deleterious SNPs of <i>FGF4</i> Gene and Their Impacts on Protein Structure, Function and Bladder Cancer Prognosis

In-Silico Analysis of Deleterious SNPs of <i>FGF4</i> Gene and Their Impacts on Protein Structure, Function and Bladder Cancer Prognosis

Dysregulation of fibroblast growth factors is linked to the pathogenesis of bladder cancer. The role of FGF1 and FGF3 is evident in bladder cancer; however, the role of FGF4 is vague. Despite being reported that FGF4 interacts with FGF1 and FGF3 in MAPK pathways, its pathogenesis and mechanism of ac...

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Bibliographic Details
Main Authors: Ee Chen Lim, Shu Wen Lim, Kenneth JunKai Tan, Maran Sathiya, Wan Hee Cheng, Kok-Song Lai, Jiun-Yan Loh, Wai-Sum Yap
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Life
Subjects:
FGF4
bladder cancer
prognosis
biomarkers
in-silico analysis
Online Access:https://www.mdpi.com/2075-1729/12/7/1018

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