First detection of dengue virus in the saliva of immunocompetent murine model

First detection of dengue virus in the saliva of immunocompetent murine model

The lack of an experimental animal model for the study of dengue pathogenesis is a limiting factor for the development of vaccines and drugs. In previous studies, our group demonstrated the susceptibility of BALB/c mice to infection by dengue virus (DENV) 1 and 2, and the virus was successfully isol...

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Bibliographic Details
Main Authors: Arthur da Costa Rasinhas, Marcos Alexandre Nunes da Silva, Gabriela Cardoso Caldas, Fernanda Cunha Jácome, Raphael Leonardo, Flávia Barreto dos Santos, Priscila Conrado Guerra Nunes, Ortrud Monika Barth, Debora Ferreira Barreto-Vieira
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2018-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
dengue 4
saliva
BALB/c mice
immunocompetent murine model
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000400400&lng=en&tlng=en

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