TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells

TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells

Metabolism of oxidative stress is necessary for cellular survival. We have previously utilized the zebrafish as a model of the oxidative stress response. In this study, we found that gata1-expressing erythroid cells contributed to a significant proportion of total-body oxidative stress when animals...

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Bibliographic Details
Main Authors: Ashley C. Kramer, Jenna Weber, Ying Zhang, Jakub Tolar, Ying Y. Gibbens, Margaret Shevik, Troy C. Lund
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Stem Cell Reports
Subjects:
erythroid precursors
oxidative stress
tp53
zebrafish
reactive oxygen species
mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116303150

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