Differences in Toxic Response Induced by Three Variants of the Diarrheic Shellfish Poisoning Phycotoxins in Human Intestinal Epithelial Caco-2 Cells

Differences in Toxic Response Induced by Three Variants of the Diarrheic Shellfish Poisoning Phycotoxins in Human Intestinal Epithelial Caco-2 Cells

Diarrheic shellfish poisoning (DSP) is caused by the consumption of shellfish contaminated with a group of phycotoxins that includes okadaic acid (OA), dinophysistoxin-1 (DTX-1), and dinophysistoxin-2 (DTX-2). These toxins are inhibitors of serine/threonine protein phosphatases 1 (PP1) and 2A (PP2A)...

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Bibliographic Details
Main Authors: Antoine Huguet, Olivia Drapeau, Fanny Rousselet, Hélène Quenault, Valérie Fessard
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Toxins
Subjects:
phycotoxins
Caco-2 cells
transcriptomics
toxicity
okadaic acid
diarrheic shellfish poisoning
Online Access:https://www.mdpi.com/2072-6651/12/12/783

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