Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells

Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells

Abstract Background Current studies have demonstrated that DODAC/PHO-S (Dioctadecyldimethylammonium Chloride/Synthetic phosphoethanolamine) liposomes induces cytotoxicity in Hepa1c1c7 and B16F10 murine tumor cells, with a higher proportion than PHO-S. Therefore, our aim was to evaluate the potential...

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Bibliographic Details
Main Authors: Arthur Cássio de Lima Luna, Greice Kelle Viegas Saraiva, Gilberto Orivaldo Chierice, Henrique Hesse, Durvanei Augusto Maria
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
Liposomes
Nanomedicine
Hepatocellular carcinoma
Antitumoral alkylphospholipids
Online Access:http://link.springer.com/article/10.1186/s40360-018-0225-2

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