Indole-2-Carboxamide Derivative LG25 Inhibits Triple-Negative Breast Cancer Growth By Suppressing Akt/mTOR/NF-κB Signalling Pathway

Indole-2-Carboxamide Derivative LG25 Inhibits Triple-Negative Breast Cancer Growth By Suppressing Akt/mTOR/NF-κB Signalling Pathway

Xiaohong Xu,1 Vinothkumar Rajamanickam,1 Sheng Shu,1 Zhoudi Liu,1 Tao Yan,1 Jinxin He,1 Zhiguo Liu,1 Guilong Guo,2 Guang Liang,1 Yi Wang1 1Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, People’s Republic of China;...

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Bibliographic Details
Main Authors: Xu X, Rajamanickam V, Shu S, Liu Z, Yan T, He J, Guo G, Liang G, Wang Y
Format: Article
Language:English
Published: Dove Medical Press 2019-10-01
Series:Drug Design, Development and Therapy
Subjects:
Indole analog
triple negative breast cancer
cell cycle arrest
apoptosis
Akt
mTOR
Online Access:https://www.dovepress.com/indole-2-carboxamide-derivative-lg25-inhibits-triple-negative-breast-c-peer-reviewed-article-DDDT

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