First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.

<h4>Background</h4>Dengue's emergence in West Africa was typified by the Burkina Faso outbreaks in 2016 and 2017, the nation's largest to date. In both years, we undertook three-month surveys of Aedes populations in or near the capital city Ouagadougou, where the outbreaks were...

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Main Authors: Athanase Badolo, Aboubacar Sombié, Félix Yaméogo, Dimitri W Wangrawa, Aboubakar Sanon, Patricia M Pignatelli, Antoine Sanon, Mafalda Viana, Hirotaka Kanuka, David Weetman, Philip J McCall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010059
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author Athanase Badolo
Aboubacar Sombié
Félix Yaméogo
Dimitri W Wangrawa
Aboubakar Sanon
Patricia M Pignatelli
Antoine Sanon
Mafalda Viana
Hirotaka Kanuka
David Weetman
Philip J McCall
author_facet Athanase Badolo
Aboubacar Sombié
Félix Yaméogo
Dimitri W Wangrawa
Aboubakar Sanon
Patricia M Pignatelli
Antoine Sanon
Mafalda Viana
Hirotaka Kanuka
David Weetman
Philip J McCall
author_sort Athanase Badolo
collection DOAJ
description <h4>Background</h4>Dengue's emergence in West Africa was typified by the Burkina Faso outbreaks in 2016 and 2017, the nation's largest to date. In both years, we undertook three-month surveys of Aedes populations in or near the capital city Ouagadougou, where the outbreaks were centered.<h4>Methodology</h4>In 1200LG (urban), Tabtenga (peri-urban) and Goundry (rural) localities, we collected indoor and outdoor resting mosquito adults, characterized larval habitats and containers producing pupae and reared immature stages to adulthood in the laboratory for identification. All mosquito adults were identified morphologically. Host species (from which bloodmeals were taken) were identified by PCR. Generalized mixed models were used to investigate relationships between adult or larval densities and multiple explanatory variables.<h4>Results</h4>From samples in 1,780 houses, adult Ae. aegypti were significantly more abundant in the two urban localities (Tabtenga and 1200 LG) in both years than in the rural site (Goundry), where Anopheles spp. were far more common. Results from adult collections indicated a highly exophilic and anthropophilic (>90% bloodmeals of human origin) vector population, but with a relatively high proportion of bloodfed females caught inside houses. Habitats producing most pupae were waste tires (37% of total pupae), animal troughs (44%) and large water barrels (30%). While Stegomyia indices were not reliable indicators of adult mosquito abundance, shared influences on adult and immature stage densities included rainfall and container water level, collection month and container type/purpose. Spatial analysis showed autocorrelation of densities, with a partial overlap in adult and immature stage hotspots.<h4>Conclusion</h4>Results provide an evidence base for the selection of appropriate vector control methods to minimize the risk, frequency and magnitude of future outbreaks in Ouagadougou. An integrated strategy combining community-driven practices, waste disposal and insecticide-based interventions is proposed. The prospects for developing a regional approach to arbovirus control in West Africa or across Africa are discussed.
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spelling doaj.art-d51a0cbce205419aabf6f38f13ff7a4a2022-12-22T03:06:49ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352022-07-01167e001005910.1371/journal.pntd.0010059First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.Athanase BadoloAboubacar SombiéFélix YaméogoDimitri W WangrawaAboubakar SanonPatricia M PignatelliAntoine SanonMafalda VianaHirotaka KanukaDavid WeetmanPhilip J McCall<h4>Background</h4>Dengue's emergence in West Africa was typified by the Burkina Faso outbreaks in 2016 and 2017, the nation's largest to date. In both years, we undertook three-month surveys of Aedes populations in or near the capital city Ouagadougou, where the outbreaks were centered.<h4>Methodology</h4>In 1200LG (urban), Tabtenga (peri-urban) and Goundry (rural) localities, we collected indoor and outdoor resting mosquito adults, characterized larval habitats and containers producing pupae and reared immature stages to adulthood in the laboratory for identification. All mosquito adults were identified morphologically. Host species (from which bloodmeals were taken) were identified by PCR. Generalized mixed models were used to investigate relationships between adult or larval densities and multiple explanatory variables.<h4>Results</h4>From samples in 1,780 houses, adult Ae. aegypti were significantly more abundant in the two urban localities (Tabtenga and 1200 LG) in both years than in the rural site (Goundry), where Anopheles spp. were far more common. Results from adult collections indicated a highly exophilic and anthropophilic (>90% bloodmeals of human origin) vector population, but with a relatively high proportion of bloodfed females caught inside houses. Habitats producing most pupae were waste tires (37% of total pupae), animal troughs (44%) and large water barrels (30%). While Stegomyia indices were not reliable indicators of adult mosquito abundance, shared influences on adult and immature stage densities included rainfall and container water level, collection month and container type/purpose. Spatial analysis showed autocorrelation of densities, with a partial overlap in adult and immature stage hotspots.<h4>Conclusion</h4>Results provide an evidence base for the selection of appropriate vector control methods to minimize the risk, frequency and magnitude of future outbreaks in Ouagadougou. An integrated strategy combining community-driven practices, waste disposal and insecticide-based interventions is proposed. The prospects for developing a regional approach to arbovirus control in West Africa or across Africa are discussed.https://doi.org/10.1371/journal.pntd.0010059
spellingShingle Athanase Badolo
Aboubacar Sombié
Félix Yaméogo
Dimitri W Wangrawa
Aboubakar Sanon
Patricia M Pignatelli
Antoine Sanon
Mafalda Viana
Hirotaka Kanuka
David Weetman
Philip J McCall
First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.
PLoS Neglected Tropical Diseases
title First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.
title_full First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.
title_fullStr First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.
title_full_unstemmed First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.
title_short First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.
title_sort first comprehensive analysis of aedes aegypti bionomics during an arbovirus outbreak in west africa dengue in ouagadougou burkina faso 2016 2017
url https://doi.org/10.1371/journal.pntd.0010059
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