Pharmaceutical Impact of Houttuynia Cordata and Metformin Combination on High-Fat-Diet-Induced Metabolic Disorders: Link to Intestinal Microbiota and Metabolic Endotoxemia

Pharmaceutical Impact of Houttuynia Cordata and Metformin Combination on High-Fat-Diet-Induced Metabolic Disorders: Link to Intestinal Microbiota and Metabolic Endotoxemia

Purpose: Metformin and Houttuynia cordata are representative anti-diabetic therapeutic agents in western and oriental medicinal fields, respectively. The present study examined the therapeutic effects of houttuynia cordata extract (HCE) and metformin in combination in a dysmetabolic mouse model.Meth...

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Bibliographic Details
Main Authors: Jing-Hua Wang, Shambhunath Bose, Na Rae Shin, Young-Won Chin, Young Hee Choi, Hojun Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Endocrinology
Subjects:
Houttuynia cordata
type 2 diabetes
high fat diet
gut microbiota
endotoxin
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00620/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00620/full

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