Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital

Introduction: Type 2 diabetes mellitus (T2DM) is a non-communicable disease with a high prevalence in Indonesia. T2DM is caused by insulin resistance and relative insulin deficiency. One of the therapy for T2DM is insulin administration which is injected into the subcutaneous tissue. The absorption...

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Main Authors: Amilia Putri Larasati, Jongky Hendro Prajitno, Bambang Purwanto
Format: Article
Language:English
Published: Faculty of Medicine, Universitas Airlangga 2023-08-01
Series:Current Internal Medicine Research and Practice Surabaya Journal
Subjects:
Online Access:https://e-journal.unair.ac.id/CIMRJ/article/view/49154
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author Amilia Putri Larasati
Jongky Hendro Prajitno
Bambang Purwanto
author_facet Amilia Putri Larasati
Jongky Hendro Prajitno
Bambang Purwanto
author_sort Amilia Putri Larasati
collection DOAJ
description Introduction: Type 2 diabetes mellitus (T2DM) is a non-communicable disease with a high prevalence in Indonesia. T2DM is caused by insulin resistance and relative insulin deficiency. One of the therapy for T2DM is insulin administration which is injected into the subcutaneous tissue. The absorption of insulin in the subcutaneous tissue is influenced by many factors, one of which is the thickness of subcutaneous fat. This study aimed to determine the correlation between the skinfold thickness of T2DM patients with the total daily dose of insulin needed every day. Methods: This was an observational analytic study using a cross-sectional design to analyze the correlation between subcutaneous fat thickness represented by skinfold thickness and the total daily dose of insulin of T2DM patients. Measurement of skinfold thickness was carried out on the triceps using a skinfold caliper. Data on the patient's total daily dose of insulin were obtained from medical records. Results: A total of 53 patients were included in this study. The patient's mean triceps skinfold thickness was 26.29±8.72 mm. The mean total daily dose of insulin was 40.96±18.01 IU. The results of the Spearman Rank correlation test showed a significant correlation between skinfold thickness on the triceps and the patient's total daily dose of insulin (p<0.05). Conclusion: The higher the skinfold thickness, the greater the dose of insulin needed by the patient.
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spelling doaj.art-d520227f21db490cb417e35fd10097db2023-11-07T07:56:51ZengFaculty of Medicine, Universitas AirlanggaCurrent Internal Medicine Research and Practice Surabaya Journal2721-544X2023-08-014210.20473/cimrj.v4i2.4915447264Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General HospitalAmilia Putri Larasati0Jongky Hendro PrajitnoBambang PurwantoUniversitas AirlanggaIntroduction: Type 2 diabetes mellitus (T2DM) is a non-communicable disease with a high prevalence in Indonesia. T2DM is caused by insulin resistance and relative insulin deficiency. One of the therapy for T2DM is insulin administration which is injected into the subcutaneous tissue. The absorption of insulin in the subcutaneous tissue is influenced by many factors, one of which is the thickness of subcutaneous fat. This study aimed to determine the correlation between the skinfold thickness of T2DM patients with the total daily dose of insulin needed every day. Methods: This was an observational analytic study using a cross-sectional design to analyze the correlation between subcutaneous fat thickness represented by skinfold thickness and the total daily dose of insulin of T2DM patients. Measurement of skinfold thickness was carried out on the triceps using a skinfold caliper. Data on the patient's total daily dose of insulin were obtained from medical records. Results: A total of 53 patients were included in this study. The patient's mean triceps skinfold thickness was 26.29±8.72 mm. The mean total daily dose of insulin was 40.96±18.01 IU. The results of the Spearman Rank correlation test showed a significant correlation between skinfold thickness on the triceps and the patient's total daily dose of insulin (p<0.05). Conclusion: The higher the skinfold thickness, the greater the dose of insulin needed by the patient.https://e-journal.unair.ac.id/CIMRJ/article/view/49154type 2 diabetes mellitusinsulin total daily dosetddskinfold thicknesssubcutaneous fat
spellingShingle Amilia Putri Larasati
Jongky Hendro Prajitno
Bambang Purwanto
Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital
Current Internal Medicine Research and Practice Surabaya Journal
type 2 diabetes mellitus
insulin total daily dose
tdd
skinfold thickness
subcutaneous fat
title Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital
title_full Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital
title_fullStr Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital
title_full_unstemmed Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital
title_short Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital
title_sort correlation between skinfold thickness and total daily dose of insulin in patient with type 2 diabetes mellitus in dr soetomo general hospital
topic type 2 diabetes mellitus
insulin total daily dose
tdd
skinfold thickness
subcutaneous fat
url https://e-journal.unair.ac.id/CIMRJ/article/view/49154
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