3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q
OBJECTIVES/SPECIFIC AIMS: 1. To evaluate the effects of masculinizing chest reconstruction on the quality of life of female-to-male transgender individuals. 2. To develop and validate a quality of life survey for female-to-male transgender individuals undergoing masculinizing chest reconstruction ge...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2019-03-01
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| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S205986611900284X/type/journal_article |
| _version_ | 1811156669468508160 |
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| author | Adrienne Kennedy Andre Alcon Esther Kim |
| author_facet | Adrienne Kennedy Andre Alcon Esther Kim |
| author_sort | Adrienne Kennedy |
| collection | DOAJ |
| description | OBJECTIVES/SPECIFIC AIMS: 1. To evaluate the effects of masculinizing chest reconstruction on the quality of life of female-to-male transgender individuals. 2. To develop and validate a quality of life survey for female-to-male transgender individuals undergoing masculinizing chest reconstruction gender-affirming surgery. METHODS/STUDY POPULATION:. We developed and refined the GENDER-Q using focus groups and exploratory interviews with FTM individuals that were recorded, transcribed, and coded. All consenting FTM patients undergoing chest reconstruction at UCSF Parnassus Medical center between 2017-2019 who meet World Professional Association for Transgender Health (WPATH) criteria for gender dysphoria will be enrolled in the study. The GENDER-Q will be co-administered with the WHO Quality of Life-BREF survey pre-operatively, 6 weeks post-operatively, and one year post-operatively through REDCAP, an online survey database. RESULTS/ANTICIPATED RESULTS: Approximately 70 patients will be enrolled in the study. Preliminary results detect statistically significant mean quality of life post-operative improvements in all three sections (Physical Health, Gender Presentation, Psychological Health) of the GENDER-Q at 6-week follow up that is maintained at one-year (p< 0.005). Statistically significant improvements were similarly achieved and maintained with the WHO QOL-BREF survey (p< 0.05). The mean reported improvement from baseline to follow-up appears to be more pronounced in the GENDER-Q survey compared to WHO QOL-BREF. The median time to complete the pre and post-operative surveys was 10 minutes. Calculation of Cronbach’s (0.67-0.81) and the Pearson Correlation Coefficient for each section revealed excellent internal validity. DISCUSSION/SIGNIFICANCE OF IMPACT: There are few studies assessing quality of life outcomes in transgender patients undergoing gender-affirming surgeries. A standardized and validated assessment tool will provide the means for which data can be pooled in large multi-center studies. Providing further evidence to support the positive health outcomes of gender-affirming surgeries can lead to broader access and reduce healthcare disparities among transgender populations. |
| first_indexed | 2024-04-10T04:55:12Z |
| format | Article |
| id | doaj.art-d520e17a4eca45b2a75299b152cc0925 |
| institution | Directory Open Access Journal |
| issn | 2059-8661 |
| language | English |
| last_indexed | 2024-04-10T04:55:12Z |
| publishDate | 2019-03-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj.art-d520e17a4eca45b2a75299b152cc09252023-03-09T12:30:29ZengCambridge University PressJournal of Clinical and Translational Science2059-86612019-03-01312512510.1017/cts.2019.2843527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-QAdrienne Kennedy0Andre Alcon1Esther Kim2University Of California, San FranciscoUniversity Of California, San FranciscoUniversity Of California, San FranciscoOBJECTIVES/SPECIFIC AIMS: 1. To evaluate the effects of masculinizing chest reconstruction on the quality of life of female-to-male transgender individuals. 2. To develop and validate a quality of life survey for female-to-male transgender individuals undergoing masculinizing chest reconstruction gender-affirming surgery. METHODS/STUDY POPULATION:. We developed and refined the GENDER-Q using focus groups and exploratory interviews with FTM individuals that were recorded, transcribed, and coded. All consenting FTM patients undergoing chest reconstruction at UCSF Parnassus Medical center between 2017-2019 who meet World Professional Association for Transgender Health (WPATH) criteria for gender dysphoria will be enrolled in the study. The GENDER-Q will be co-administered with the WHO Quality of Life-BREF survey pre-operatively, 6 weeks post-operatively, and one year post-operatively through REDCAP, an online survey database. RESULTS/ANTICIPATED RESULTS: Approximately 70 patients will be enrolled in the study. Preliminary results detect statistically significant mean quality of life post-operative improvements in all three sections (Physical Health, Gender Presentation, Psychological Health) of the GENDER-Q at 6-week follow up that is maintained at one-year (p< 0.005). Statistically significant improvements were similarly achieved and maintained with the WHO QOL-BREF survey (p< 0.05). The mean reported improvement from baseline to follow-up appears to be more pronounced in the GENDER-Q survey compared to WHO QOL-BREF. The median time to complete the pre and post-operative surveys was 10 minutes. Calculation of Cronbach’s (0.67-0.81) and the Pearson Correlation Coefficient for each section revealed excellent internal validity. DISCUSSION/SIGNIFICANCE OF IMPACT: There are few studies assessing quality of life outcomes in transgender patients undergoing gender-affirming surgeries. A standardized and validated assessment tool will provide the means for which data can be pooled in large multi-center studies. Providing further evidence to support the positive health outcomes of gender-affirming surgeries can lead to broader access and reduce healthcare disparities among transgender populations.https://www.cambridge.org/core/product/identifier/S205986611900284X/type/journal_article |
| spellingShingle | Adrienne Kennedy Andre Alcon Esther Kim 3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q Journal of Clinical and Translational Science |
| title | 3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q |
| title_full | 3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q |
| title_fullStr | 3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q |
| title_full_unstemmed | 3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q |
| title_short | 3527 Quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes: The GENDER-Q |
| title_sort | 3527 quantifying the psychosocial benefits of masculinizing chest reconstruction in transgender men with patient reported outcomes the gender q |
| url | https://www.cambridge.org/core/product/identifier/S205986611900284X/type/journal_article |
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