Post-COVID-19 endogenous endophthalmitis case series and review of literature

Purpose: To describe a series of post-coronavirus disease 2019 (COVID-19) endogenous endophthalmitis (EE) patients from a multispecialty tertiary hospital in North India. Methods: A retrospective chart review including all consecutive cases with EE following confirmed COVID-19 disease from July 2020...

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Main Authors: Ramanuj Samanta, Sreeram Jayaraj, Sanjeev K Mittal, Jyoti Kumari, Aarshi Naharwal, Ajai Agrawal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=12;spage=3677;epage=3683;aulast=Samanta
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author Ramanuj Samanta
Sreeram Jayaraj
Sanjeev K Mittal
Jyoti Kumari
Aarshi Naharwal
Ajai Agrawal
author_facet Ramanuj Samanta
Sreeram Jayaraj
Sanjeev K Mittal
Jyoti Kumari
Aarshi Naharwal
Ajai Agrawal
author_sort Ramanuj Samanta
collection DOAJ
description Purpose: To describe a series of post-coronavirus disease 2019 (COVID-19) endogenous endophthalmitis (EE) patients from a multispecialty tertiary hospital in North India. Methods: A retrospective chart review including all consecutive cases with EE following confirmed COVID-19 disease from July 2020 to June 2021. Results: Seven eyes of four patients (three female and one male) were included. Two patients had confirmed bilateral fungal (Aspergillus sp.) EE and two patients had presumed fungal EE (one bilateral and one unilateral). Three of these four patients received systemic steroids as part of COVID-19 treatment previously. Five eyes were managed with initial intravitreal injection (IVI), followed by pars plana vitrectomy (PPV), and two eyes were managed with only IVI. All patients received systemic antifungal agents. Intraocular inflammation resolved in all eyes with treatment. One patient of EE also developed voriconazole-induced transient visual hallucination, which resolved on discontinuing the medication. Conclusion: This case series represents a series of EE cases following COVID-19 disease or its sequelae or as a result of prior treatment for COVID-19. Ophthalmologists and physicians must be vigilant about these complications and initiate prompt management at the earliest.
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spelling doaj.art-d525b5ccf8f340e3907da619a09a30ec2024-03-25T14:37:55ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-0171123677368310.4103/IJO.IJO_3079_22Post-COVID-19 endogenous endophthalmitis case series and review of literatureRamanuj SamantaSreeram JayarajSanjeev K MittalJyoti KumariAarshi NaharwalAjai AgrawalPurpose: To describe a series of post-coronavirus disease 2019 (COVID-19) endogenous endophthalmitis (EE) patients from a multispecialty tertiary hospital in North India. Methods: A retrospective chart review including all consecutive cases with EE following confirmed COVID-19 disease from July 2020 to June 2021. Results: Seven eyes of four patients (three female and one male) were included. Two patients had confirmed bilateral fungal (Aspergillus sp.) EE and two patients had presumed fungal EE (one bilateral and one unilateral). Three of these four patients received systemic steroids as part of COVID-19 treatment previously. Five eyes were managed with initial intravitreal injection (IVI), followed by pars plana vitrectomy (PPV), and two eyes were managed with only IVI. All patients received systemic antifungal agents. Intraocular inflammation resolved in all eyes with treatment. One patient of EE also developed voriconazole-induced transient visual hallucination, which resolved on discontinuing the medication. Conclusion: This case series represents a series of EE cases following COVID-19 disease or its sequelae or as a result of prior treatment for COVID-19. Ophthalmologists and physicians must be vigilant about these complications and initiate prompt management at the earliest.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=12;spage=3677;epage=3683;aulast=Samantaaspergillus endophthalmitiscovid-19endogenous endophthalmitisfungal endophthalmitisvoriconazole hallucination
spellingShingle Ramanuj Samanta
Sreeram Jayaraj
Sanjeev K Mittal
Jyoti Kumari
Aarshi Naharwal
Ajai Agrawal
Post-COVID-19 endogenous endophthalmitis case series and review of literature
Indian Journal of Ophthalmology
aspergillus endophthalmitis
covid-19
endogenous endophthalmitis
fungal endophthalmitis
voriconazole hallucination
title Post-COVID-19 endogenous endophthalmitis case series and review of literature
title_full Post-COVID-19 endogenous endophthalmitis case series and review of literature
title_fullStr Post-COVID-19 endogenous endophthalmitis case series and review of literature
title_full_unstemmed Post-COVID-19 endogenous endophthalmitis case series and review of literature
title_short Post-COVID-19 endogenous endophthalmitis case series and review of literature
title_sort post covid 19 endogenous endophthalmitis case series and review of literature
topic aspergillus endophthalmitis
covid-19
endogenous endophthalmitis
fungal endophthalmitis
voriconazole hallucination
url http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=12;spage=3677;epage=3683;aulast=Samanta
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