Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old
Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many year...
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Format: | Article |
Language: | English |
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Elsevier
2023-03-01
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Series: | Oral and Maxillofacial Surgery Cases |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214541922000487 |
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author | Brenden J. Manley Timothy W. Neal Shyam Indrakanti Thomas Schlieve |
author_facet | Brenden J. Manley Timothy W. Neal Shyam Indrakanti Thomas Schlieve |
author_sort | Brenden J. Manley |
collection | DOAJ |
description | Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors’ knowledge, this is the youngest patient with MRONJ reported in the literature. |
first_indexed | 2024-04-10T07:14:30Z |
format | Article |
id | doaj.art-d527edcb0ac24242b1df359c229daebc |
institution | Directory Open Access Journal |
issn | 2214-5419 |
language | English |
last_indexed | 2024-04-10T07:14:30Z |
publishDate | 2023-03-01 |
publisher | Elsevier |
record_format | Article |
series | Oral and Maxillofacial Surgery Cases |
spelling | doaj.art-d527edcb0ac24242b1df359c229daebc2023-02-26T04:27:17ZengElsevierOral and Maxillofacial Surgery Cases2214-54192023-03-0191100289Spontaneous medication-related osteonecrosis of the jaws in a 23-year-OldBrenden J. Manley0Timothy W. Neal1Shyam Indrakanti2Thomas Schlieve3Department of Surgery, Division of Oral and Maxillofacial Surgery, UT Southwestern/Parkland Memorial Hospital, USACorresponding author. DDS, UTSW Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, , USA.; Department of Surgery, Division of Oral and Maxillofacial Surgery, UT Southwestern/Parkland Memorial Hospital, USADepartment of Surgery, Division of Oral and Maxillofacial Surgery, UT Southwestern/Parkland Memorial Hospital, USADepartment of Surgery, Division of Oral and Maxillofacial Surgery, UT Southwestern/Parkland Memorial Hospital, USAMedication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors’ knowledge, this is the youngest patient with MRONJ reported in the literature.http://www.sciencedirect.com/science/article/pii/S2214541922000487AntiresorptiveOsteonecrosisBisphosphonate |
spellingShingle | Brenden J. Manley Timothy W. Neal Shyam Indrakanti Thomas Schlieve Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old Oral and Maxillofacial Surgery Cases Antiresorptive Osteonecrosis Bisphosphonate |
title | Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old |
title_full | Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old |
title_fullStr | Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old |
title_full_unstemmed | Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old |
title_short | Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old |
title_sort | spontaneous medication related osteonecrosis of the jaws in a 23 year old |
topic | Antiresorptive Osteonecrosis Bisphosphonate |
url | http://www.sciencedirect.com/science/article/pii/S2214541922000487 |
work_keys_str_mv | AT brendenjmanley spontaneousmedicationrelatedosteonecrosisofthejawsina23yearold AT timothywneal spontaneousmedicationrelatedosteonecrosisofthejawsina23yearold AT shyamindrakanti spontaneousmedicationrelatedosteonecrosisofthejawsina23yearold AT thomasschlieve spontaneousmedicationrelatedosteonecrosisofthejawsina23yearold |