Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen <named-content content-type="genus-species">Candida auris</named-content>

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen <named-content content-type="genus-species">Candida auris</named-content>

ABSTRACT Fungal infections are a major contributor to infectious disease-related deaths worldwide. Recently, global emergence of the fungal pathogen Candida auris has caused considerable concern because most C. auris isolates are resistant to fluconazole, the most commonly administered antifungal, a...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Kali R. Iyer, Luke Whitesell, John A. Porco, Thomas Henkel, Lauren E. Brown, Nicole Robbins, Leah E. Cowen
Format: Artikel
Sprache:English
Veröffentlicht: American Society for Microbiology 2020-04-01
Schriftenreihe:mBio
Schlagworte:
Candida auris
antifungal
apoptosis
autophagy
cell death
rocaglate
Online Zugang:https://journals.asm.org/doi/10.1128/mBio.03329-19

Online

https://journals.asm.org/doi/10.1128/mBio.03329-19

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