Metabolic Potential of the Gut Microbiome Is Significantly Impacted by Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation Recipients

Metabolic Potential of the Gut Microbiome Is Significantly Impacted by Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation Recipients

Allogeneic hematopoietic stem cell transplantation (aHSCT) is a putative curative treatment for malignant hematologic disorders. During transplantation, the immune system is suppressed/eradicated through a conditioning regimen (non-myeloablative or myeloablative) and replaced with a donor immune sys...

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Bibliographic Details
Main Authors: Mette Jørgensen, Jens C. Nørgaard, Emma E. Ilett, Ramtin Z. Marandi, Marc Noguera-Julian, Roger Paredes, Daniel D. Murray, Jens Lundgren, Cameron Ross MacPherson, Henrik Sengeløv
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
allogeneic hematopoietic stem cell transplantation (aHSCT)
conditioning regimen
metabolic potential
gut microbiome
whole genome sequencing
Online Access:https://www.mdpi.com/1422-0067/23/19/11115

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