Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers

Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers

A potential target of precision nutrition in cancer therapeutics is the micronutrient selenium (Se). Se is metabolized and incorporated as the amino acid selenocysteine (Sec) into 25 human selenoproteins, including glutathione peroxidases (GPXs) and thioredoxin reductases (TXNRDs), among others. Bot...

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Bibliographic Details
Main Authors: Briana K. Shimada, Sydonie Swanson, Pamela Toh, Lucia A. Seale
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomolecules
Subjects:
selenium
ferroptosis
cancer
solid tumors
selenium metabolism
Online Access:https://www.mdpi.com/2218-273X/12/11/1581

Internet

https://www.mdpi.com/2218-273X/12/11/1581

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