Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE)
Abstract Background In former studies, parity was associated with adverse cardiovascular outcomes in parents. This study aims to extend the limited existing data regarding the association between the number of children and heart disease and/or stroke in a large longitudinal study in different Europe...
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | BMC Public Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12889-023-17254-7 |
| _version_ | 1827632874705125376 |
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| author | Carolin Girschik Susanne Stolpe Bernd Kowall |
| author_facet | Carolin Girschik Susanne Stolpe Bernd Kowall |
| author_sort | Carolin Girschik |
| collection | DOAJ |
| description | Abstract Background In former studies, parity was associated with adverse cardiovascular outcomes in parents. This study aims to extend the limited existing data regarding the association between the number of children and heart disease and/or stroke in a large longitudinal study in different European countries in both men and women. Methods For 42 075 subjects (18 080 men, 23 995 women; median age 58 years (interquartile range: 53 to 65)) from 19 European countries and Israel in the Survey of Health, Ageing and Retirement in Europe (SHARE), odds ratios (OR) for the association between number of children and incident self-reported heart disease and/or stroke (HDS) were estimated using logistic regression analyses. Persons with one or two children were used as reference. The final model was adjusted for baseline age, sex, education, region, and marital status. All analyses were stratified by sex. Results Women with seven or more children had the highest OR for the association between the number of children and incident HDS (OR = 2.12 [95% CI: 1.51 to 2.98]), while men with six children showed the highest OR (OR = 1.62 [1.13 to 2.33]). Stratified by education, across all education levels, men and women with five or more children had the highest ORs for this association. The highest OR was observed in both women and men in the group with primary education (OR = 1.66 [1.29 to 2.15] and OR = 1.60 [1.19 to 2.14], respectively). Stratified by region, both men and women with five or more children showed the highest ORs in Southern Europe (OR = 2.07 [1.52 to 2.82] and OR = 1.75 [1.25 to 2.44], respectively). Conclusion In this long-term follow-up study in various countries in Europe and Israel we found a positive association between number of children and incident HDS. This association was more pronounced in lower educated subjects and showed regional variations. |
| first_indexed | 2024-03-09T14:51:41Z |
| format | Article |
| id | doaj.art-d5304cb0f289473dbf2bd4182b2a19e2 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-03-09T14:51:41Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-d5304cb0f289473dbf2bd4182b2a19e22023-11-26T14:28:33ZengBMCBMC Public Health1471-24582023-11-0123111110.1186/s12889-023-17254-7Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE)Carolin Girschik0Susanne Stolpe1Bernd Kowall2Institute of Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of EssenInstitute of Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of EssenInstitute of Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of EssenAbstract Background In former studies, parity was associated with adverse cardiovascular outcomes in parents. This study aims to extend the limited existing data regarding the association between the number of children and heart disease and/or stroke in a large longitudinal study in different European countries in both men and women. Methods For 42 075 subjects (18 080 men, 23 995 women; median age 58 years (interquartile range: 53 to 65)) from 19 European countries and Israel in the Survey of Health, Ageing and Retirement in Europe (SHARE), odds ratios (OR) for the association between number of children and incident self-reported heart disease and/or stroke (HDS) were estimated using logistic regression analyses. Persons with one or two children were used as reference. The final model was adjusted for baseline age, sex, education, region, and marital status. All analyses were stratified by sex. Results Women with seven or more children had the highest OR for the association between the number of children and incident HDS (OR = 2.12 [95% CI: 1.51 to 2.98]), while men with six children showed the highest OR (OR = 1.62 [1.13 to 2.33]). Stratified by education, across all education levels, men and women with five or more children had the highest ORs for this association. The highest OR was observed in both women and men in the group with primary education (OR = 1.66 [1.29 to 2.15] and OR = 1.60 [1.19 to 2.14], respectively). Stratified by region, both men and women with five or more children showed the highest ORs in Southern Europe (OR = 2.07 [1.52 to 2.82] and OR = 1.75 [1.25 to 2.44], respectively). Conclusion In this long-term follow-up study in various countries in Europe and Israel we found a positive association between number of children and incident HDS. This association was more pronounced in lower educated subjects and showed regional variations.https://doi.org/10.1186/s12889-023-17254-7ParityNumber of childrenHeart diseaseStrokeCardiovascular disease |
| spellingShingle | Carolin Girschik Susanne Stolpe Bernd Kowall Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE) BMC Public Health Parity Number of children Heart disease Stroke Cardiovascular disease |
| title | Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE) |
| title_full | Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE) |
| title_fullStr | Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE) |
| title_full_unstemmed | Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE) |
| title_short | Association between number of children and incident heart disease and stroke in parents – results from the Survey of Health, Ageing and Retirement in Europe (SHARE) |
| title_sort | association between number of children and incident heart disease and stroke in parents results from the survey of health ageing and retirement in europe share |
| topic | Parity Number of children Heart disease Stroke Cardiovascular disease |
| url | https://doi.org/10.1186/s12889-023-17254-7 |
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