Stability of Signaling Pathways during Aging—A Boolean Network Approach

Stability of Signaling Pathways during Aging—A Boolean Network Approach

Biological pathways are thought to be robust against a variety of internal and external perturbations. Fail-safe mechanisms allow for compensation of perturbations to maintain the characteristic function of a pathway. Pathways can undergo changes during aging, which may lead to changes in their stab...

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Bibliographic Details
Main Authors: Julian Daniel Schwab, Lea Siegle, Silke Daniela Kühlwein, Michael Kühl, Hans Armin Kestler
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Biology
Subjects:
Boolean networks
aging
reconstruction
stability
Online Access:https://www.mdpi.com/2079-7737/6/4/46

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