Wolf Creek XVII Part 7: Mechanical circulatory support
Introduction: Failure to restore spontaneous circulation remains a major cause of death for cardiac arrest (CA) patients. Mechanical circulatory support, specifically extracorporeal cardiopulmonary resuscitation (ECPR), has emerged as a feasible and efficacious rescue strategy for selected refractor...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Resuscitation Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666520423001364 |
| _version_ | 1827615754676076544 |
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| author | Cindy H. Hsu George Trummer Jan Belohlavek Demetris Yannopoulos Jason A. Bartos |
| author_facet | Cindy H. Hsu George Trummer Jan Belohlavek Demetris Yannopoulos Jason A. Bartos |
| author_sort | Cindy H. Hsu |
| collection | DOAJ |
| description | Introduction: Failure to restore spontaneous circulation remains a major cause of death for cardiac arrest (CA) patients. Mechanical circulatory support, specifically extracorporeal cardiopulmonary resuscitation (ECPR), has emerged as a feasible and efficacious rescue strategy for selected refractory CA patients. Methods: Mechanical Circulatory Support was one of six focus topics for the Wolf Creek XVII Conference held on June 14–17, 2023 in Ann Arbor, Michigan, USA. Conference invitees included international thought leaders and scientists in the field of CA resuscitation from academia and industry. Participants submitted via online survey knowledge gaps, barriers to translation and research priorities for each focus topic. Expert panels used the survey results and their own perspectives and insights to create and present a preliminary unranked list for each category that was debated, revised and ranked by all attendees to identify the top 5 for each category. Results: Top 5 knowledge gaps included optimal patient selection, pre-ECPR treatments, logistical and programmatic characteristics of ECPR programs, generalizability and effectiveness of ECPR, and prevention of reperfusion injury. Top 5 barriers to translation included cost/resource limitations, technical challenges, collaboration across multiple disciplines, limited patient population, and early identification of eligible patients. Top 5 research priorities focused on comparing the outcomes of prehospital/rapid transport strategies vs in-hospital ECPR initiation, implementation of high-performing ECPR system vs standard care, rapid patient identification tools vs standard clinical judgment, post-cardiac arrest bundled care vs no bundled care, and standardized ECPR clinical protocol vs routine care. Conclusion: This overview can serve as an innovative guide to transform the care and outcome of patients with refractory CA. |
| first_indexed | 2024-03-09T09:16:11Z |
| format | Article |
| id | doaj.art-d535541365c74a9dba340d2b79c61654 |
| institution | Directory Open Access Journal |
| issn | 2666-5204 |
| language | English |
| last_indexed | 2024-03-09T09:16:11Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Resuscitation Plus |
| spelling | doaj.art-d535541365c74a9dba340d2b79c616542023-12-02T07:06:58ZengElsevierResuscitation Plus2666-52042023-12-0116100493Wolf Creek XVII Part 7: Mechanical circulatory supportCindy H. Hsu0George Trummer1Jan Belohlavek2Demetris Yannopoulos3Jason A. Bartos4Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA; The Max Harry Weil Institute for Critical Care Research and Innovation, University of Michigan, Ann Arbor, MI, USA; Corresponding author at: Department of Emergency Medicine, University of Michigan Medical School, NCRC B026-309N, 2800 Plymouth Road, Ann Arbor, MI 48109-2800, USA.Department of Cardiovascular Surgery, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany2nd Department of Medicine – Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech RepublicDepartment of Medicine-Cardiovascular Division, University of Minnesota, Minneapolis, MN, USADepartment of Medicine-Cardiovascular Division, University of Minnesota, Minneapolis, MN, USAIntroduction: Failure to restore spontaneous circulation remains a major cause of death for cardiac arrest (CA) patients. Mechanical circulatory support, specifically extracorporeal cardiopulmonary resuscitation (ECPR), has emerged as a feasible and efficacious rescue strategy for selected refractory CA patients. Methods: Mechanical Circulatory Support was one of six focus topics for the Wolf Creek XVII Conference held on June 14–17, 2023 in Ann Arbor, Michigan, USA. Conference invitees included international thought leaders and scientists in the field of CA resuscitation from academia and industry. Participants submitted via online survey knowledge gaps, barriers to translation and research priorities for each focus topic. Expert panels used the survey results and their own perspectives and insights to create and present a preliminary unranked list for each category that was debated, revised and ranked by all attendees to identify the top 5 for each category. Results: Top 5 knowledge gaps included optimal patient selection, pre-ECPR treatments, logistical and programmatic characteristics of ECPR programs, generalizability and effectiveness of ECPR, and prevention of reperfusion injury. Top 5 barriers to translation included cost/resource limitations, technical challenges, collaboration across multiple disciplines, limited patient population, and early identification of eligible patients. Top 5 research priorities focused on comparing the outcomes of prehospital/rapid transport strategies vs in-hospital ECPR initiation, implementation of high-performing ECPR system vs standard care, rapid patient identification tools vs standard clinical judgment, post-cardiac arrest bundled care vs no bundled care, and standardized ECPR clinical protocol vs routine care. Conclusion: This overview can serve as an innovative guide to transform the care and outcome of patients with refractory CA.http://www.sciencedirect.com/science/article/pii/S2666520423001364Cardiac arrestMechanical circulatory supportExtracorporeal cardiopulmonary resuscitationWolf Creek Conference |
| spellingShingle | Cindy H. Hsu George Trummer Jan Belohlavek Demetris Yannopoulos Jason A. Bartos Wolf Creek XVII Part 7: Mechanical circulatory support Resuscitation Plus Cardiac arrest Mechanical circulatory support Extracorporeal cardiopulmonary resuscitation Wolf Creek Conference |
| title | Wolf Creek XVII Part 7: Mechanical circulatory support |
| title_full | Wolf Creek XVII Part 7: Mechanical circulatory support |
| title_fullStr | Wolf Creek XVII Part 7: Mechanical circulatory support |
| title_full_unstemmed | Wolf Creek XVII Part 7: Mechanical circulatory support |
| title_short | Wolf Creek XVII Part 7: Mechanical circulatory support |
| title_sort | wolf creek xvii part 7 mechanical circulatory support |
| topic | Cardiac arrest Mechanical circulatory support Extracorporeal cardiopulmonary resuscitation Wolf Creek Conference |
| url | http://www.sciencedirect.com/science/article/pii/S2666520423001364 |
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